Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice

By Jaewon Lee, Wenzhen Duan, Mark P. Mattson. Journal of Neurochemistry, 2002

981 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/0877648632e84debb15bcb9425d2c509455b58af

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Duman
2. Fred H. Gage
3. H. van Praag
4. H. Schmidt
5. D. Abrous
6. M. Koehl
7. Eero Castrén
8. M. Le Moal

In Developmental Neuroscience

1. R. Duman
2. Fred H. Gage
3. H. van Praag
4. D. Abrous
5. H. Schmidt
6. M. Le Moal
7. M. Koehl
8. Mark P. Mattson

Citations in the corpus

• Calcium and neurodegeneration (2007, background): “For example, dietary energy restriction (Lee et al., 2002a,b; Maswood et al., 2004) and exercise (Smith & Zigmond, 2003; Vaynman & Gomez-Pinilla, 2006) can increase brain-derived neurotrophic factor (BDNF) and glial cell line-derived neuro- trophic factor (GDNF) signaling.”
• Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment (2003, background): “Yet another possibility is brain-derived neurotrophic factor (BDNF), which is downregulated by stress (Nibuya et al, 1995; Smith et al, 1995) and is reported to increase neurogenesis (Pencea et al, 2001; Lee et al, 2002).”
• BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity (2017, background): “In vivo studies showed that BDNF is involved in regulation of neurogenesis in the adult hippocampus (Katoh-Semba et al. 2002; Lee et al. 2002; Scharfman et al. 2005).”
• Brain-Derived Neurotrophic Factor and Antidepressant Drugs Have Different But Coordinated Effects on Neuronal Turnover, Proliferation, and Survival in the Adult Dentate Gyrus (2005, background): “BDNF signaling plays a role in the differentiation and survival of neuronal progenitor cells (Lee et al., 2002; Barnabe-Heider and Miller, 2003).”
• Brain metabolism in health, aging, and neurodegeneration (2017, neutral): “MCT1 has high affinity for pyruvate and also transports lactate and ketone bodies; it is present in endothelial cells (Gerhart et al, 1997), astrocytes (Bröer et al, 1997), oligodendrocytes (Lee et al, 2012), and microglia (Moreira et al, 2009).”
• Brain-derived neurotrophic factor. (2004, background): “Although some studies have concluded that the primary effect of BDNF is on proliferation (Katoh-Semba et al., 2002), other experiments suggest an important effect on survival (Lee et al., 2002).”
• Brain‐derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment (2006, background): “including the schedule of BrdU administration and the time interval between BrdU labelling and fixation (Lee et al., 2002; Sairanen et al., 2005).”
• Exercise and the brain: something to chew on (2009, background): “Caloric restriction increases the production of new neurons [57].”
• Adult neurogenesis: from precursors to network and physiology. (2005, background): “Concerning the DG, it has been shown that heterozygous BDNF knockout mice exhibit reduced proliferation and survival of BrdU-labeled cells (301), sugNEUROGENESIS IN THE ADULT BRAIN 537”
• Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. (2004, background): “BDNF knockout mice, in contrast, show impaired LTP (Korte et al., 1995; Patterson et al., 1996) and reduced neurogenesis (Lee et al., 2002).”
• Brain-derived Neurotrophic Factor Promotes Differentiation and Maturation of Adult-born Neurons Through GABAergic Transmission (2012, background): “In agreement with this view, considerable evidence links BDNF and adult neurogenesis (Lee et al., 2002b; Sairanen et al., 2005; Scharfman et al., 2005; Bergami et al., 2008; Chan et al., 2008; Li et al., 2008); however, these studies have reported conflicting results.”
• Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression (2005, background): “BDNF is required for basal neurogenesis (Lee et al., 2002) and can bemodulated by astrocytes and endothelial cells to support neuronal differentiation (Kirschenbaum”