Akt1 and Akt2 are required for αβ thymocyte survival and differentiation

By M. Juntilla, J. Wofford, M. Birnbaum, J. Rathmell, G. Koretzky. Proceedings of the National Academy of Sciences of the United States of America, 2007

124 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/07c9a24cf6610a3d566fbb4662119288c2f74f4b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Erika L. Pearce
2. Michael D. Buck
3. David O’Sullivan
4. J. Rathmell
5. Nancie J. MacIver
6. S. Kaech

In Molecular Biology

1. Nancie J. MacIver
2. Erika L. Pearce
3. J. Rathmell
4. Michael D. Buck
5. J. Wofford
6. Heather L. Wieman
7. David O’Sullivan
8. M. V. Vander Heiden

In Oncology

1. Erika L. Pearce
2. Michael D. Buck

Citations in the corpus

• Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways1 (2008, result): “Despite the continued presence of Akt2 and Akt3, which are expressed in T cells and can also regulate glucose uptake (29), glucose uptake appeared to be reduced in Akt1 / costimulated T cells compared with Akt1 / T cells (Fig.”
• T cell metabolism drives immunity (2015, background): “Increased expression of the glucose transporter Glut1 is required during this stage, and its expression is dependent on activation of the kinase Akt by PI3K (Swainson et al., 2005; Juntilla et al., 2007; Wieman et al., 2007).”