Cyclin E ablation in the mouse.

By Y. Geng, Qunyan Yu, E. Sicinska, M. Das, J. Schneider, S. Bhattacharya, W. Rideout, R. Bronson, H. Gardner, P. Sicinski. Cell, 2003

692 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/0595cda77c09e8f8b77eed69781424a3f2eac386

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Citations in the corpus

A hyperfused mitochondrial state achieved at G1–S regulates cyclin E buildup and entry into S phase (2009, background): “Regulation of cyclin E levels by hyperfused mitochondria at G1–S could explain why knockouts of mitofusins (MFN1–2) phenocopy the effects of cyclin E knockouts (24, 25).”
Cell cycle, CDKs and cancer: a changing paradigm (2009, background): “Ablation of the genes encoding cyclin E1 and cyclin E2 also results in embryonic lethality, in this case owing to specific defects in the endo-reduplication of trophoblast cell”
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms (2009, background): “Impairment in the endoreplication of megakaryocytes was also observed in the absence of cyclin E (Geng et al., 2003; Parisi et al., 2003).”
Minireview: Cyclin D1: normal and abnormal functions. (2004, background): “in spermatogenesis and trophoblast giant cell formation (87),”
Pocket proteins and cell cycle control (2005, neutral): “S progression in mouse fibroblasts (Berthet et al., 2003; Geng et al., 2003; Ortega et al., 2003; Kozar et al., 2004; Malumbres et al., 2004).”
The E2F transcriptional network: old acquaintances with new faces (2005, background): “…E2, cdk2 and the Dtype cyclins, that show tremendous resilience of the cell cycle to perturbation during animal development (Berthet et al., 2003; Geng et al., 2003; Ortega et al., 2003; Parisi et al., 2003; Kozar et al., 2004). cdk4 cycD1 p16/Ink4a RB E2F Pathway componentsAlterations in…”
Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation (2004, background): “5539”
Living with or without cyclins and cyclin-dependent kinases. (2004, background): “5 due to defects in the endoreduplication cycles that normally occur in placental trophoblast giant cells (Geng et al. 2003; Parisi et al. 2003).”
Specific arrests of spermatogenesis in genetically modified and mutant mice (2004, background): “In this respect it is interesting that cyclin E2-deficient mice also have a meiosis problem, extensive apoptosis of spermatocytes taking place especially in meiotic division (Geng et al., 2003).”
G1 cell-cycle control and cancer (2004, background): “For example, E-type cyclins are largely dispensable for mouse development (although cells lacking cyclin E have problems loading MCM onto DNA”
Preventing re-replication of chromosomal DNA (2005, background): “However, they fail to make trophoblast giant cells and megakaryocytes, which are both cell types that need to endoreduplicate to attain a >2N DNA conten”