G1 cell-cycle control and cancer

By J. Massagué. Nature, 2004

1,232 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/f2612d92f43a4ee350f39f4346df5833f4d193a8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. J. Massagué
2. A. Moustakas
3. C. Heldin
4. Steven P. Gygi
5. J. Villén
6. J. Seoane
7. Marcos Malumbres
8. D. Wotton

In Oncology

1. Marcos Malumbres
2. J. Seoane
3. J. Massagué
4. A. Moustakas
5. C. Heldin
6. M. Barbacid
7. D. Wotton
8. Changchun Xiao

Citations in the corpus

• MicroRNA control in the immune system: basic principles. (2009, background): “P21, Rbl2, E2F1, E2F2, and E2F3 regulate cell cycle progression at the G1 to S transition (Balomenos et al., 2000; Cobrinik, 2005; Field et al., 1996; Massague, 2004; Murga et al., 2001; Santiago-Raber et al., 2001; Yamasaki et al., 1996; Zhu et al., 2001).”
• Smad transcription factors. (2005, background): “2784 GENES & DEVELOPMENT and Massagué 2003; Xu and Massagué 2004).”
• Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence (2006, neutral): “dtd" [ ]> p53 limits the proliferation of primary diploid fibroblasts by inducing a state of growth arrest named replicative senescence — a process which protects against oncogenic transformation and requires integrity of the p53 tumour suppressor pathwa”
• Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase (2005, background): “Ras-MAPK signaling is also necessary to induce expression of S-phase-promoting Cdc25A phosphatase, which dephosphorylates inhibitory Cdk2 residues and activates Cdk2-cyclin E activity (45, 52).”
• Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells (2015, background): “G1 phase is a sensitive period during which cell fate decisions are made (Takahashi et al. 1995; Sherr 2000; Calegari and Huttner 2003; Massague 2004; Pauklin and Vallier 2013).”
• Luteolin, a flavonoid with potential for cancer prevention and therapy. (2008, background): “The sequential process, called cell cycle, consists of four distinct phases, G1, S, G2, and M [76].”
• Non-Smad TGF-β signals (2005, background): “The growth inhibitory pathway induced by TGF-β includes critical regulators of the G1 phase of the cell cycle, whose gene expression is modulated by Smads (Massagué, 2004).”
• Cell cycle, CDKs and cancer: a changing paradigm (2009, background): “Tumour cells accumulate mutations that result in constitutive mitogenic signalling and defective responses to anti-mitogenic signals that contribute to unscheduled proliferation”
• The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis (2007, background): “p27 inhibits the kinase activity of cyclin–cdk holoenzymes, particularly cyclin E–cdk2, resulting in cell-cycle arres”
• A quantitative atlas of mitotic phosphorylation (2008, background): “Nigg EA (2001) Mitotic kinases as regulators of cell division and its checkpoints. Nat Rev Mol Cell Biol 2:21–32. 7. Johnson SA, Hunter T (2005) Kinomics: Methods for deciphering the kinome.”