Circular RNAs are a large class of animal RNAs with regulatory potency

By Sebastian Memczak, Marvin Jens, Antigoni L Elefsinioti, F. Torti, Janna Krueger, Agnieszka Rybak, L. Maier, Sebastian D. Mackowiak, L. Gregersen, Mathias Munschauer and 6 more. Nature, 2013

7,259 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/036377e98783b4fdf7c97e4f93511b00434bc29d

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Citations in the corpus

Exosome Theranostics: Biology and Translational Medicine (2018, background): “Moreover, circRNAs can serve as sponges for microRNAs and proteins with stable, conservative, and tissue/developmental-stage-specific expression patterns [156].”
CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs (2016, background): “In eukaryotes, circRNAs arise most often through backsplicing, a process in which the 5' and 3' ends of a spliced RNA are covalently linked to form a closed RNA molecule that contains exon and/or intron sequences.(1-3) Although a few examples of circRNAs have been known for several decades, only wit”
circRNA biogenesis competes with pre-mRNA splicing. (2014, methodology): “Cotranscriptional Production of circRNAs Inspecting our own data (Memczak et al., 2013), we noticed that many circRNAs are generated from transcripts expressed in”
Advances and Trends in Omics Technology Development (2022, background): “…been successfully applied to decode miRNA-target interactions (186), identify RNA binding sites of splicing factors (187, 188), investigate epigenetic modiﬁcation-associated RNAs (189), and explore functions of ceRNAs (190), they suﬀer from several limitations that await additional improvements.”
Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches. (2016, background): “In vivo studies revealed that a CiRS-7/CDR1as overexpression leads to a similar phenotype of impaired midbrain development than that of a miR-7 knockout mouse (186).”
Circular RNA identification based on multiple seed matching (2018, methodology): “in cytoplasm [7, 8], nucleus-localized EIciRNAs were found to function as parental gene transcription activators [9].”
Circular RNA (circRNA) in Alzheimer's disease (AD) (2013, background): “Intrinsically resistant to exonucleolytic RNA decay, circRNAs appear to be enriched in mammalian brain tissues (Hansen et al., 2013; Memczak et al., 2013).”
CIRI: an efficient and unbiased algorithm for de novo circular RNA identification (2015, methodology): “Analyzing circRNAs identified from enormous RNA-seq data combined with sequencing data generated from additional samples has been adopted in several studies [11,13] and will probably continue to be a commonly used approach in further studies on circRNAs.”
Circular RNAs: analysis, expression and potential functions (2016, background): “Another circRNA named ciRS-7, or sometimes simply CDR1as, which is derived from the Cdr1 antisense locus, also probably functions as a miRNA sponge (Hansen et al., 2013; Memczak et al., 2013).”
Single-cell transcriptome sequencing: recent advances and remaining challenges (2016, methodology): “Finally, the bulk of scRNA-seq literature has focused solely on polya-denylated mRNAs; almost all published scRNA-seq protocols isolate cellular RNA by using poly-T priming, which captures only polya-denylated transcripts.”
Metazoan MicroRNAs (2018, background): “in human and mouse Cdr1as, respectively) (Hansen et al., 2013; Memczak et al., 2013; Piwecka et al., 2017).”