Quorum Sensing in Staphylococcus aureus Biofilms

By J. Yarwood, D. Bartels, E. Volper, E. P. Greenberg. Journal of Bacteriology, 2004

637 citations recorded by the source corpus.

Subfields: Infectious Diseases, Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/0246f6508aa74f22aaa437c02f98746aa6f56abf

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Citations in the corpus

Quorum sensing in staphylococci. (2008, background): “(131); agr is activated very locally during biofilm formation and clumps of agr-expressing organisms soon detach, leaving a hole in the film that is filled by new, agr-expressing organisms growing in from the periphery.”
Evolution of hypervirulence by a MRSA clone through acquisition of a transposable element (2014, methodology): “Thus, to determine if IS256 affects regulation of virulence and cytotoxin production in USA500, agr activation was examined using a reporter plasmid containing the rnaIII promoter fused to yfp (Yarwood et al., 2004).”
Biofilms as Promoters of Bacterial Antibiotic Resistance and Tolerance (2020, background): “aureus, a QS-deficient agrD mutant exhibited a biofilmspecific decrease in resistance to rifampin compared to wild type [167].”
Bacterial quorum sensing: its role in virulence and possibilities for its control. (2012, background): “One interpretation of this finding is that establishing a biofilm community at LCD allows S. aureus time to grow to HCD and, at that point, it is optimally poised to secrete virulence factors (Yarwood et al. 2004; Boles and Horswill 2008).”
Biofilm in Implant Infections: Its Production and Regulation (2005, background): “aureus the expression of agr occurs simultaneously with the detachment of the cells (47).”
Staphylococcus aureus biofilms: recent developments in biofilm dispersal (2014, background): “Non-specific mechanisms, such as the surfactant activity of phenol-soluble modulins (PSMs), are effective against most S. aureus biofilms and are reviewed elsewhere (Peschel and Otto, 2013).”
Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials. (2012, background): “cells or cell clusters by various mechanisms, is crucial for the dissemination of the bacteria to new infection sites in the human body [102,103].”
How Staphylococcus aureus biofilms develop their characteristic structure (2012, background): “After about 72 h, the USA300 WT strain showed the previously described (6) characteristic waves of detachment and regrowth (Fig.”
Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses (2010, background): “…in biofilms produced by the human pathogens A. actinomycetemcomitans, P. aeruginosa, Serratia marcescens, and S. aureus (Kaplan et al., 2003a; Yarwood et al., 2004; Koh et al., 2007; Ma et al., 2009); by the plant-associated bacteria P. putida and Chromobacterium violacium (Tolker-Nielsen et…”
Coagulase-Negative Staphylococci (2014, background): “Observed, partially conflicting findings may result from different experimental settings (385).”
Biofilms: the matrix revisited. (2005, background): “Also, dead cells have been observed in some biofilms, suggesting that cell detritus can be considered part of the extracellular matrix [14, 15 ].”
Staphylococcal biofilms (2018, background): “aureus biofilms over time and have proposed a model for agr-dependent biofilm maintenance (Yarwood et al. 2004).”
Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms (2009, background): “Furthermore, the agr system is more active in cells that have detached from the biofilm, a finding consistent with the negative regulation of biofilm formation by quorum sensing (355).”
ica and beyond: biofilm mechanisms and regulation in Staphylococcus epidermidis and Staphylococcus aureus. (2007, background): “Moreover, under different growth conditions, the influence of agr on biofilm formation can vary from positive to neutral to negative, perhaps reflecting the responsiveness of the Agr system to external environmental cues (Yarwood et al., 2004).”
Staphylococcus epidermidis – the “accidental” pathogen (2009, background): “aureus , a model has been proposed that involves agr expression in the exposed layers of a biofilm and promotes the detachment of cell clusters from the biofilm surface, thereby controlling biofilm expansio”
Quorum Sensing and Bacterial Social Interactions in Biofilms (2012, background): “nosocomial infections worldwide and causes diseases from mild skin infections to potentially fatal systemic disorders [31,45,46].”