Induction of apoptosis by cancer chemotherapy.
By S. Kaufmann, W. Earnshaw. Experimental Cell Research, 2000
1,317 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/002bb05e0faad3a577595b892b3563bdf33897fb
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Citations in the corpus
- Immunotherapy and chemotherapy — a practical partnership (2005, background): “Although chemotherapeutic drugs induce their primary damage in many different ways, most of them induce apoptosis not only in vitro but also in vivo”
- ROS, stress‐activated kinases and stress signaling in cancer (2002, background): “Nevertheless, the evidence linking apoptosis and therapy (Kaufmann and Earnshaw, 2000; Lowe and Lin, 2000) is sufficient to warrant discussion of the modulation of apoptosis-related signaling pathways in connection with anticancer therapy responsiveness.”
- The cellular and molecular basis of hyperthermia. (2002, background): “As genetic alteration of these genes were found to contribute to malignant transformation and disease progression in various hematological and solid malignancies, basic research on apoptosis was propelled during the last decade [130,136–140].”
- MicroRNA: Biogenesis, Function and Role in Cancer (2010, background): “It is hypothesized that BCL2 repression via miR15b/miR16-2 reduces a cell’s sensitivity to drug-induced apoptosis [263, 270-272].”
- miR‐15b and miR‐16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells (2008, background): “chondrial pathway plays a predominant role in chemotherapyinduced apoptosis.(44) BCL2 is well acknowledged as a critical reg-”
- Targeting Free Radicals in Oxidative Stress-Related Human Diseases. (2017, background): “Anticancer drugs such as paclitaxel and docetaxel (both members of the taxane group) promote the release of cytochrome c from mitochondria which induces cell death; it is thought that these drugs may interfere with the electron transport chain and lead to the formation of superoxide radical anions [”
- Chemotherapy-Associated Oxidative Stress: Impact on Chemotherapeutic Effectiveness (2004, background): “The 2 major cellular pathways of drug-induced apoptosis are the mitochondrial pathway, initiated by release of cytochrome c, and the CD95 death receptor pathway, initiated by ligation of the death receptor by its ligand CD95L (Figure 6).(14,57,58) Following the initiating event, the apoptotic proces”