G. Lessene
Molecular Biology · 2008–2018
A researcher in the Science corpus: 5 papers; trusts 4 researchers and is trusted by 1 researcher here, as inferred from the citation graph.
Subfields
- Molecular Biology — 124 citations into it; #12,911 of 17,773 by trust here, #6,960 by citations
- Immunology — 26 citations into it
- Organic Chemistry — 8 citations into it
Whom G. Lessene trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- Stefan Schreiber
- Beth Levine
- A. Strasser
- Stephen W. Fesik
- R. Youle
- Simon N. Willis
- Lin Chen
- D. Hanahan
Who trusts G. Lessene overall
Papers from G. Lessene's perspective
Ordered by how strongly the researchers G. Lessene trusts endorse each paper. Same corpus, a different order for every researcher.
- The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. (Molecules and Cells)
- An inhibitor of Bcl-2 family proteins induces regression of solid tumours (Nature)
- Promoting apoptosis as a strategy for cancer drug discovery (Nature Reviews. Cancer)
- Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA (Cell)
- Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (Cell)
- Caspases and their substrates (Cell Death and Differentiation)
- Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. (Cancer Cell)
- The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. (Cancer Cell)
- Autophagy in the pathogenesis of disease. (Cell)
- Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes (Nature Cell Biology)
Their papers
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy (2013) — 3,023 citations
- The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models (2016) — 971 citations
- BCL-2 family antagonists for cancer therapy (2008) — 623 citations
- BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis (2018) — 936 citations
- Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (2014) — 921 citations