T. Pirtskhalava
Physiology · 2015–2019
A researcher in the Science corpus: 10 papers; trusts 1 researcher and is trusted by 2 researchers here, as inferred from the citation graph.
Subfields
- Physiology — 121 citations into it; #1,180 of 2,276 by trust here, #245 by citations
Whom T. Pirtskhalava trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts T. Pirtskhalava overall
Papers from T. Pirtskhalava's perspective
Ordered by how strongly the researchers T. Pirtskhalava trusts endorse each paper. Same corpus, a different order for every researcher.
- Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence (Nature Cell Biology)
- Senescence of activated stellate cells limits liver fibrosis (Cell)
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders (Nature)
- Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas (Nature)
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence (Nature Communications)
- Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture). (American Journal of Physiology. Heart and Circulatory Physiology)
- From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
- Blinded by the Light: The Growing Complexity of p53. (Cell)
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors (Aging Cell)
- Cellular Senescence in Aging Primates (Science)
Their papers
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors (2016) — 1,003 citations
- Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease (2019) — 1,153 citations
- Senolytics Improve Physical Function and Increase Lifespan in Old Age (2018) — 1,970 citations
- Fisetin is a senotherapeutic that extends health and lifespan (2018) — 892 citations
- Physiological frailty index (PFI): quantitative in-life estimate of individual biological age in mice (2017) — 671 citations
- Targeting cellular senescence prevents age-related bone loss in mice (2017) — 1,011 citations
- Cellular senescence mediates fibrotic pulmonary disease (2017) — 1,412 citations
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice (2016) — 685 citations
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (2015) — 2,184 citations
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age (2015) — 792 citations