Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture).

By M. Félétou, P. M. Vanhoutte. American Journal of Physiology. Heart and Circulatory Physiology, 2006

797 citations recorded by the source corpus.

Subfields: Biochemistry, Endocrinology, Diabetes and Metabolism, Physiology

View Paper: https://www.semanticscholar.org/paper/cbfa10a2cb6cf109fdcbeb6d9a25dcf8b26b14d6

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In Physiology

1. J. Kirkland
2. T. Tchkonia
3. Nathan K. LeBrasseur
4. T. Pirtskhalava
5. Yi Zhu
6. S. Khosla
7. D. Jurk
8. M. Félétou

Citations in the corpus

• Endothelial dysfunction - a major mediator of diabetic vascular disease. (2013, background): “Functional impairment of the vascular endothelium is found in all forms of cardiovascular disease [3, 12] and also in people with insulin resistance, obesity and type 2 diabetes [18].”
• Endothelial dysfunction and vascular disease – a 30th anniversary update (2017, background): “…role of NO is curtailed, the inflammatory response (Ross 1999) that leads to atherosclerosis is initiated (Vanhoutte 1988, 1996, 1997, 2000, 2002, 2009b, L€uescher et al. 1993, Li et al. 2002b, Vallance 2003, Cooke 2004, Voetsch et al. 2004, F el etou & Vanhoutte 2006b, Vanhoutte et al. 2009).”
• Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives (2011, background): “, endothelium-derived contracting factors such as thromboxane A2, free radicals/ROS, endothelin (ET), and angiotensin II] (159, 174, 175, 236).”
• Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice (2016, background): “…M. Roos,1,a Bin Zhang,1,a Allyson K. Palmer,2,a Mikolaj B. Ogrodnik,2,3 Tamar Pirtskhalava,2 Nassir M. Thalji,1 Michael Hagler,1 Diana Jurk,3 Leslie A. Smith,1 Grace Casaclang-Verzosa,1 Yi Zhu,2 Marissa J. Schafer,2 Tamara Tchkonia,2 James L. Kirkland2,4 and Jordan D. Miller1,2,4 1Department…”
• The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs (2015, background): “4D), a complex amalgam of nitric oxide, endothelium-derived hyperpolarizing factors, and other vasoactive substances (Feletou & Vanhoutte, 2006), D+Q, yielded physiologically important and consistent improvements in vascular smooth muscle sensitivity to nitroprusside (Fig.”