James E. Crowe Jr.
Molecular Biology · 2010–2021
A researcher in the Science corpus: 14 papers; trusts 11 researchers and is trusted by 0 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 128 citations into it
- Materials Chemistry — 33 citations into it
- Computational Biology & Bioinformatics — 28 citations into it
- Computational Theory and Mathematics — 11 citations into it
Whom James E. Crowe Jr. trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
- Colin A. Smith
- Tanja Kortemme
- Roland L. Dunbrack
- Andrew Leaver-Fay
- Amelie Stein
- Brian Kuhlman
- David Baker
- Gavin E. Crooks
Papers from James E. Crowe Jr.'s perspective
Ordered by how strongly the researchers James E. Crowe Jr. trusts endorse each paper. Same corpus, a different order for every researcher.
- Macromolecular modeling with rosetta.
- Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction.
- Native protein sequences are close to optimal for their structures.
- Rotamer libraries in the 21st century.
- Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions.
- Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design
- Computational design of proteins targeting the conserved stem region of influenza hemagglutinin
- WebLogo: a sequence logo generator.
- The Rosetta all-atom energy function for macromolecular modeling and design
- Improvements to Robotics-Inspired Conformational Sampling in Rosetta
Their papers
- Tackling soil diversity with the assembly of large, complex metagenomes (2014) — 308 citations
- Improving Loop Modeling of the Antibody Complementarity-Determining Region 3 Using Knowledge-Based Restraints (2016) — 24 citations
- Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition (2020) — 934 citations
- Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences (2015) — 39 citations
- Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site (2013) — 148 citations
- Multi-state design of flexible proteins predicts sequences optimal for conformational change (2019) — 26 citations
- Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies (2021) — 866 citations
- Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein (2021) — 384 citations
- Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 (2020) — 698 citations
- Potently neutralizing and protective human antibodies against SARS-CoV-2 (2020) — 1,004 citations
- Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses (2019) — 27 citations
- Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus (2017) — 90 citations
- Proof of principle for epitope-focused vaccine design (2014) — 544 citations
- Structural basis of pre-existing immunity to the 2009 H1N1 pandemic influenza virus (2010) — 641 citations