Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

By M. Hong, Peter S. Lee, Ryan M. B. Hoffman, Xueyong Zhu, Jens C. Krause, N. S. Laursen, Sung-il Yoon, Langzhou Song, L. Tussey, James E. Crowe Jr. and 2 more. 2013

148 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology, Radiology, Nuclear Medicine and Imaging

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Nicholas C. Wu
2. Ian A. Wilson

In Molecular Biology

1. Tong Li
2. Robert J. Pantazes
3. Costas D. Maranas
4. Ian A. Wilson
5. Nicholas C. Wu
6. Bernhard O. Palsson
7. David S. Wishart
8. Ali R. Zomorrodi

In Radiology, Nuclear Medicine and Imaging

1. Tong Li
2. Costas D. Maranas
3. Robert J. Pantazes
4. Nicholas C. Wu

Citations in the corpus

• OptMAVEn – A New Framework for the de novo Design of Antibody Variable Region Models Targeting Specific Antigen Epitopes (2014, background): “This mode of receptor mimicry has also been observed in related broadly neutralizing antibodies CH65 [45] and 5J8 [60], which use HCDR3 insertion, and S139/1, which uses HCDR2 insertion.”
• A perspective on the structural and functional constraints for immune evasion: insights from the influenza virus (2017, background): “Besides the small binding footprint that is preferred for bnAbs to specifically target the relatively small RBS [58], which thereby restricts the interaction to the most conserved region of this site, the neutralizing activity of RBS-targeted bnAbs is promoted by an avidity effect [69, 71, 76].”