D. Leahy

Oncology · Molecules and Cells · 2001–2011

A researcher in the Science corpus: 8 papers; trusts 3 researchers and is trusted by 6 researchers here, as inferred from the citation graph.

Subfields

• Oncology — 51 citations into it; #624 of 1,698 by trust here, #445 by citations
• Molecular Biology — 48 citations into it; #17,431 of 17,773 by trust here, #5,452 by citations
• Materials Chemistry — 6 citations into it

Whom D. Leahy trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. T. C. Terwilliger

Who trusts D. Leahy overall

1. J. Baselga

Papers from D. Leahy's perspective

Ordered by how strongly the researchers D. Leahy trusts endorse each paper. Same corpus, a different order for every researcher.

1. PROCHECK: a program to check the stereochemical quality of protein structures
2. Likelihood-enhanced fast rotation functions.
3. Refinement of macromolecular structures by the maximum-likelihood method.
4. Use of TLS parameters to model anisotropic displacements in macromolecular refinement.
5. Untangling the ErbB signalling network (Nature reviews. Molecular cell biology)
6. Crystallography & NMR system: A new software suite for macromolecular structure determination.
7. Automated MAD and MIR structure solution
8. Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT.
9. The conformational plasticity of protein kinases. (Cell)
10. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. (Molecules and Cells)

Their papers

• Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling (2011) — 76 citations
• Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains (2001) — 493 citations
• Mechanism of activation and inhibition of the HER4/ErbB4 kinase. (2008) — 196 citations
• Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab (2003) — 1,641 citations
• EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. (2003) — 793 citations
• Functionally significant insulin-like growth factor I receptor mutations in centenarians (2008) — 730 citations
• Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. (2004) — 1,125 citations
• An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. (2003) — 955 citations