Phenolic Compounds

By Milena Morandi Vuolo, V. S. Lima, M. M. Júnior. Bioactive Compounds, 2019

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Abstract Phenolic compounds are the most abundant antioxidants in the human diet. They have a considerable structural diversity, characterized by the hydroxyl groups on aromatic rings. According to the number of phenol rings and the structural elements that bind rings to one another, such compounds are grouped and classified as simple phenols, phenolic acids, flavonoids, xanthones, stilbenes, and lignans. Each group has different mechanisms of action correlated to a structural specificity, which confer the antioxidant properties to the compounds. They act mainly in scavenging reactive species of oxygen, nitrogen, and chlorine or can also chelate metal ions, acting in both the initiation stage and in the propagation of the oxidative process. The most common in vitro methods used to evaluate antioxidant activity of phenolic compounds are in vitro methods which are based on single electron transfer reaction or single hydrogen atom transfer reaction.

Subfields: Biochemistry, Molecular Biology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/fff1f6b8d63fe1f45b5fe494219511fa103e0a52

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