A gene regulatory network orchestrates neural crest formation

By T. Sauka-Spengler, M. Bronner‐Fraser. Nature reviews. Molecular cell biology, 2008

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Epithelial-mesenchymal transitions: insights from development (2012, background): “Neural crest cells then delaminate and migrate as mesenchymal-like cells in defined routes before reaching their target sites, where they differentiate into various derivatives (Sauka-Spengler and Bronner-Fraser, 2008; Minoux and Rijli, 2010; Theveneau and Mayor, 2011).”
Signaling mechanisms of the epithelial-mesenchymal transition (2014, background): “Other development processes mediated by joint signals from TGF-β and other signaling pathways include gastrulation and neural crest delamination, which involve a triad of TGF-β, Wnt, and FGF signaling (249, 250).”
Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress (2018, background): “and multi-potent population of cells that can differentiate into diverse cell types (Sauka-Spengler and Bronner-Fraser, 2008).”
Epithelial-mesenchymal transitions in development and disease. (2009, background): “Although organized in a hierarchy, these factors can also regulate expression of each other (Sauka-Spengler and Bronner-Fraser, 2008).”
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. (2009, neutral): “Studies by many laboratories have provided a general picture of the gene regulatory network that operates during neural crest development (62).”