Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.
By H. Acloque, M. Bronner‐Fraser, M. Nieto, M. Adams, K. Fishwick, Angela Nieto. Journal of Clinical Investigation, 2009
1,332 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/a5887f963eb3886e19b9c0781ea329e9226168b2
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
Citations in the corpus
- Cellular and molecular mechanisms of renal fibrosis (2011, background): “Epithelial–mesenchymal transition Another source of matrix-producing cells could be tubular epithelium that undergoes EMT, a cell phenotypic conversion process that occurs during embryonic development, tumor metastasis and organ fibrosis”
- Inflammation and EMT: an alliance towards organ fibrosis and cancer progression (2009, background): “This can be regarded as the reactivation of a developmental programme designed to endow cells with migratory and invasive properties and with amazing survival properties, crucial for migratory cells to reach their sometimes far destinations within the embryo (Acloque et al, 2009).”
- Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation. (2010, background): “Intensive studies revealed that transcriptional factors, such as Snail, Slug, and Twist, regulate EMT process (21, 22).”
- TGF-β1 Signaling and Tissue Fibrosis. (2018, background): “Similarly, mesenchymal cells can derive from ectoderm (e.g., facial cartilage) and mesoderm (e.g., skeletal muscle) (Acloque et al. 2009; Thiery et al. 2009).”
- Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast (2011, background): “The epithelial-mesenchymal transition (EMT) affects critical steps of morphogenesis by interconverting epithelial cell types into cells with mesenchymal attributes (Acloque et al., 2009; Thiery et al., 2009).”