Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry.

By M. Ehrich, Matthew R. Nelson, P. Stanssens, M. Zabeau, T. Liloglou, G. Xinarianos, C. Cantor, J. Field, D. van den Boom. Proceedings of the National Academy of Sciences of the United States of America, 2005

835 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ff51c3752225dd4fcd2c15d69bfbbb99d12e31cd

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In Molecular Biology

Citations in the corpus

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia (2010, methodology): “Validation of HELP data was performed by matrix-assisted laser desorption/ionization timeof-flight mass spectrometry using EpiTYPER by MassARRAY (Sequenom, San Diego, CA) on bisulfite-converted DNA as previously described (Ehrich et al., 2005).”
DNA methylation analysis by pyrosequencing (2007, methodology): “Methods with improved quantitative resolution based on matrix-assisted laser desorption/ionization mass spectrometr”
Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation (2013, methodology): “Quantitative DNA Methylation Analysis by MassARRAY EpiTYPER Validation of the three most significant loci (AHRRcg05575921, ALPP/ALPPL2- cg21566642 and F2RL3cg03636183) was carried out by MALDI-TOF mass spectrometry using EpiTYPER by MassARRAY (Sequenom, San Diego, CA) as previously described [53].”
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells (2010, methodology): “Validation of HELP findings was performed by matrix-assisted laser desorption ionization/time-of-flight (MALDI-TOF) mass spectrometry using EpiTyper by MassARRAY (Sequenom) on bisulfite-converted DNA following manufacturer's instruction”
Principles and challenges of genome-wide DNA methylation analysis (2010, methodology): “An alternative approach to sequencing or hybridization is detection by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometr”
Epigenetic gene promoter methylation at birth is associated with child’s later adiposity (2011, methodology): “amplification of bisulfite-treated DNA was followed by in vitro transcription and analysis by matrix-assisted laser desorption ionization time-of-flight (MALDITOF) mass spectrometry (27,28).”
Mass spectrometry tools for the classification and identification of bacteria (2010, background): “The various approaches for MALDI-based resequencing rely on the analysis of base-specific fragments that are derived from microbial nucleic acid”
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. (2007, methodology): “Customer service for DNA methylation analysis was performed by Sequenom, Inc., using the MassARRAY system as previously described (Ehrich et al. 2005).”
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. (2009, methodology): “The quantitative nature, accuracy and reproducibility of this method have been shown extensively (20,43,44).”
Persistent epigenetic differences associated with prenatal exposure to famine in humans (2008, methodology): “Departments of aMolecular Epidemiology, cMedical Statistics, and dGerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands; bHubert Department of Global Health, Rollins School of Public Health, Emory University Atlanta, GA 30322; eDepartment of Epidemiology, Mailman Scho”
Oct4-induced pluripotency in adult neural stem cells. (2009, methodology): “The MassCLEAVE biochemistry was performed as previously described (Ehrich et al., 2005).”