DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.
By E. Tobi, L. Lumey, R. P. Talens, D. Kremer, Hein Putter, A. Stein, P. Slagboom, B. Heijmans. Human Molecular Genetics, 2009
1,160 citations recorded by the source corpus.
Subfields: Molecular Biology, Pediatrics, Perinatology and Child Health
View Paper: https://www.semanticscholar.org/paper/2c1727b28aade567e54ae3dcc68a1b9f0a722349
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In Molecular Biology
In Pediatrics, Perinatology and Child Health
- Mark A. Hanson
- Peter D. Gluckman
- K. Lillycrop
- G. Burdge
- Chris Cooper
- Keith M. Godfrey
- Barry M. Popkin
- P. Ellison
Citations in the corpus
- Mechanistic Pathways of Sex Differences in Cardiovascular Disease. (2017, background): “Dutch study showed that famine-induced epigenetic modifications occurred in a sex-specific manner (389).”
- Immune Dysfunction as a Cause and Consequence of Malnutrition (2016, background): “For example, maternal malnutrition during the Dutch Hunger Winter modified the infant IL10 locus as well as genes associated with growth hormones, cholesterol transport, lipid metabolism, and the HPA axis that persisted decades later [35].”
- Epigenetic gene promoter methylation at birth is associated with child’s later adiposity (2011, background): “In vitro fertilization increases risk of imprinting disorders (44), and methylation effects on imprinted genes have been reported in offspring of mothers exposed to famine during various periods of pregnancy (45,46), but with no associations with phenotype reported.”
- Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus (2016, background): “During Dutch famine, sex-dimorphic alterations of epigenetic profiles were seen in offspring exposed to malnutrition (Table 2) (155).”