Oct4-induced pluripotency in adult neural stem cells.

By J. Kim, V. Sebastiano, Guangming Wu, M. Araúzo-Bravo, P. Sasse, L. Gentile, Kinarm Ko, D. Ruau, M. Ehrich, D. van den Boom and 8 more. Cell, 2009

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Induced pluripotency: history, mechanisms, and applications. (2010, background): “Consistent with this notion, somatic cells that express other reprogramming factors endogenously do not require administration of the corresponding exogenous factor(s), as has been demonstrated for neural stem cells that can be converted into iPSCs by Oct4 alone (Table 2; JB Kim et al. 2009a).”
Senescence impairs successful reprogramming to pluripotent stem cells. (2009, background): “Indeed, Oct4 alone is sufficient to directly reprogram mouse neural stem cells to pluripotency (Kim et al., 2009).”
Epigenetic memory in induced pluripotent stem cells (2010, result): “Neural progenitor-derived iPSC were most similar to fESC, consistent with evidence that such cells can be reprogrammed with fewer transcription factors 38 .”
A fresh look at iPS cells. (2009, methodology): “Kim et al. (2009) have generated iPS cells from adult mouse neural stem cells using Oct3/4 alone.”