Faculty Opinions recommendation of High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity.

By W. Blessing. 2009

937 citations recorded by the source corpus.

Subfields: Physiology

View Paper: https://www.semanticscholar.org/paper/fe66ef1da8e5b4ebff2e383b58f4aa55105c7f12

How researchers see this paper

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In Physiology

1. S. Kajimura
2. B. Spiegelman
3. P. Seale
4. L. Sidossis
5. H. Ohno
6. Kosaku Shinoda
7. E. Rosen
8. R. Scarpulla

Citations in the corpus

• Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans (2014, background): “Further, BAT is associated with leanness (5) and euglycemia (4,6,7), suggesting that, unlike other adipose tissue depots, BAT may be protective against obesity and diabetes.”
• Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist (2015, background): “One appealing new target for treatment is the activation of brown adipose tissue (BAT), an organ recently found to be functional in adult humans (van Marken Lichtenbelt et al., 2009; Cypess et al., 2009; Virtanen et al., 2009; Zingaretti et al., 2009; Saito et al., 2009).”
• Brown and beige fat: Physiological roles beyond heat-generation (2015, background): “…that humans have substantial depots of UCP1+ adipose cells and that these tissues are activated to take up glucose by cold or b-adrenergic agonist treatment (Cypess et al., 2009, 2014, 2015; Nedergaard et al., 2007; Saito et al., 2009; van Marken Lichtenbelt et al., 2009; Virtanen et al., 2009).”
• Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells (2012, background): “humans have significant amounts of active brown fat deposits [3,4,5,6,7,8,9].”
• FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine (2013, background): “inversely correlated with overall adiposity, which suggests that variations in the amount or activity of BAT are related to the susceptibility for weight gain in humans [2–6].”
• Recruited brown adipose tissue as an antiobesity agent in humans. (2013, neutral): “Recent studies using fluorodeoxyglucose-PET (FDG-PET) in combination with CT revealed that adult humans have considerable amounts of BAT (2–5).”