Cellular Antioxidant Effects of Atorvastatin In Vitro and In Vivo

By S. Wassmann, Ulrich Laufs, K. Müller, C. Konkol, K. Ahlbory, A. Bäumer, W. Linz, M. Böhm, G. Nickenig. Arteriosclerosis, Thrombosis and Vascular Biology, 2002

624 citations recorded by the source corpus.

Subfields: Inorganic Chemistry, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/fdb23699e096cf8eee1eb422a27dc2fa6f59b61a

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In Oncology

1. P. Ridker

In Surgery

1. P. Ridker
2. Peter Libby
3. L. Melvin

Citations in the corpus

• NADPH Oxidases in Cardiovascular Health and Disease (2006, neutral): “The local levels of O • (cid:1) (together with molecules such as hemoglobin and antioxidants such as the SODs, which all influence influence NO bioactivity ) are potentially important in the spatial”
• Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms (2005, background): “By inhibiting Rac isoprenylation, statins can lead to a reduction in NADPH oxidase assembly and, consequently, generation of RO”
• Vascular NAD(P)H oxidases: specific features, expression, and regulation. (2003, methodology): “These effects were reversed specifically by the addition of mevalonate (214, 215), confirming that statins acted via inhibition of the biosynthesis of this lipid precursor.”