Networks and crosstalk: integrin signalling spreads

By M. Schwartz, M. Ginsberg. Nature Cell Biology, 2002

811 citations recorded by the source corpus.

Subfields: Cell Biology, Immunology and Allergy, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/fd73a9f7113c969fa012d045fb62514c2583c409

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Citations in the corpus

Mechanical models for living cells--a review. (2006, background): “Studies have also shown that many biological processes, such as growth, differentiation, migration, and even apoptosis (programmed cell death) are influenced by changes in cell shape and structural integrity (Chen et al., 1997; Boudreau and Bissell, 1998; Huang and Ingber, 1999; Schwartz and Ginsber”
Focal adhesion kinase: the first ten years (2003, background): “In the interim, much progress has been made regarding integrin signaling and the role of protein tyrosine kinases, and FAK in particular, in this pathway (Miranti and Brugge, 2002; Schwartz and Ginsberg, 2002).”
Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions (2002, background): “These events depend on the binding of integrin to the extracellular matrix, and assembly of focal adhesions, which are complexes comprising scaffolding and signalling proteins organized by adhesion to the extracellular matri”
The regulation of tendon stem cell differentiation by the alignment of nanofibers. (2010, background): “It is known that cell–matrix interaction, which is mediated by integrin, plays an important role in regulating cell functions such as migration, proliferation, and differentiation [32].”
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004, methodology): “Using various protocols, murine HSCs can be purified close to homogeneity by fluorescent-activated cell sorting (FACS) (Smith et al. 1991; Goodell et al. 1996).”
An extracellular matrix microarray for probing cellular differentiation (2005, background): “In addition to the well-described crosstalk between integrin and growth factor signalin”
Mutant p53 drives invasion by promoting integrin recycling. (2009, background): “There is considerable crosstalk between integrins and the signaling of receptor tyrosine kinases (RTKs) (Schwartz and Ginsberg, 2002), so we examined the effect of mutant p53 expression on integrin and EGFR signaling in trypsinized cells that were either allowed to remain in suspension or were…”
Integrin signalling during tumour progression (2004, background): “Third, FAK–SFK signalling promotes disassembly of focal adhesion”
Engineering microscale topographies to control the cell–substrate interface (2012, background): “Integrins also transmit ECM signals more directly through its physical connection with the actin filaments of the cell [71,72].”