Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.

By Johannes Rinn, Michael Kertesz, Jordon K. Wang, S. Squazzo, Xiao Xu, Samantha A. Brugmann, L. H. Goodnough, Jill A. Helms, Peggy J. Farnham, Eran Segal and 1 more. Cell, 2007

4,352 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/fb11e430be99acfd0ea966a463aab85c6bca4a6c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Howard Y. Chang
2. David P. Bartel
3. Johannes Rinn
4. Ling-Ling Chen
5. Igor Ulitsky
6. John S. Mattick
7. Richard A. Young
8. Marcel E. Dinger

In Molecular Biology

1. Howard Y. Chang
2. Ling-Ling Chen
3. Johannes Rinn
4. David P. Bartel
5. John S. Mattick
6. Igor Ulitsky
7. Richard A. Young
8. A. Bird

Citations in the corpus

• NONCODEv4: exploring the world of long non-coding RNA genes (2013, background): “For example, a transcript variant of the lncRNA gene termed HOTAIR (31) was assigned identifier ‘NR_003716’ in RefSeq.”
• Control of somatic tissue differentiation by the long non-coding RNA TINCR (2012, neutral): “For secondary structure analysis, the following TINCR radiolabelled RT primers were used: (1) 59-CCTTGATGTGGTAGCGCTTCCAGCGC-39; (2) 59-AGACA GGGCACCCAGGGCCCCAAGAGG-39; (3) 59-TGTCCTGGGCAAGAGCGGA AGTGCCTC-39; (4) 59-AAAGCAGCTCCAGCAGGTCTGCCTGCCG-39; (5) 59-GGGCACACAGTGGGTCTCTGGGGACAAAG-39; (6) 59-TACT”
• Revisiting the principles of microRNA target recognition and mode of action (2009, background): “: the HOX loci use several ncRNAs for their complex epigenetic regulatio”
• NONCODE 2016: an informative and valuable data source of long non-coding RNAs (2015, background): “ncRNAs are as important as protein-coding genes to cellular functions (5,6).”
• Epigenetic modifications and human disease (2010, background): “HOTAIR is a lincRNA transcribed from the HOXC cluster that represses genes in the HOXD cluster by recruiting the histone methyltransferase PRC2 (ref”
• lincRNAs: Genomics, Evolution, and Mechanisms (2013, neutral): “…et al., 2011; Gomez et al., 2013; Grote et al., 2013), LDS1 (Tsai et al., 2010), and the polycomb complexes PRC1 (Schoeftner et al., 2006) and PRC2 (Rinn et al., 2007; Zhao et al., 2008; Tsai et al., 2010; Grote et al., 2013; Klattenhoff et al., 2013), although the extent to which some of these…”
• Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene (2010, background): “2-kb ncRNA involved in the repression of the HOX loci and promoting cancer metastasis (Rinn et al., 2007; Gupta et al., 2010).”