Translational control in stress and apoptosis

By M. Holcik, Nahum Sonenberg. Nature reviews. Molecular cell biology, 2005

1,451 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f9f12520069076ea4b684a458059075a7ec7a796

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In Cardiology and Cardiovascular Medicine

In Molecular Biology

Citations in the corpus

Systematic Functional Annotation and Visualization of Biological Networks (2016, background): “The growth benefit conferred by inactive ribosomes during chemical stress is consistent with the downregulation of ribosomal gene expression as part of the environmental stress response (ESR) program (Warner, 1999; Holcik and Sonenberg, 2005).”
Abiotic Stress in Plants and Metabolic Responses (2013, background): “For example, nitrogen and carbon assimilation are impaired in maize during salt stress and potassium-deficiency stress; the synthesis of free amino acids, chlorophyll, and protein are also affected [26-28].”
Hydrogen peroxide sensing, signaling and regulation of transcription factors (2014, background): “Normal physiological protein synthesis is mostly done via CAPdependent mechanisms while protein synthesis of stress response factors is done via IRESs, which can induce cells to rapidly produce sufficient amounts of protein in response to the stress [169].”
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate (2006, background): “IRE1 is both a protein kinase and an endoribonucleas”
Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes (2012, background): “When cells encounter environmental stress, ribosomes help to coodinate the expression of stress-response genes (Holcik and Sonenberg, 2005).”
Translational control of long-lasting synaptic plasticity and memory. (2009, neutral): “Cellular IRESes were identified in the 5 0 UTR of mRNAs encoding proteins which need to be synthesized under stress condition such as apoptosis, virus infection, hypoxia, nutrient deprivation, etc., where cap-dependent translation is impaired (Holcik and Sonenberg, 2005).”
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL (2016, neutral): “Of note, cap-dependent translation is inhibited in response to various forms of cellular stress 29 .”
Dendritic mRNA: transport, translation and function (2007, methodology): “Inhibition of cap-dependent translation appears to favour the use of IRES-mediated translatio”
Quantifying the dynamics of IRES and cap translation with single-molecule resolution in live cells (2020, background): “Extensive studies have shown that both viral and some endogenous IRES sequences remain translationally active during cellular stress 13,15,16 .”
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. (2008, background): “Many of these IRES-containing mRNAs are regulated during stress situations such as differentiation or apoptosis (Hellen and Sarnow 2001; Holcik and Sonenberg 2005).”
From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health (2007, neutral): “to manage stress conditions effectively (140, 327).”
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients (2016, background): “The ER stress response is developed to protect cells from various stress conditions, such as hypoxia, nutrient deprivation, and low pH, and includes three major signaling cascades initiated by three protein sensors: protein kinase RNA-like ER kinase (PERK), inositol-requiring enzyme1 (IRE1), andATF6”
The eIF2α kinases: their structures and functions (2013, neutral): “Compared with control at the level of transcription, control of protein synthesis holds the key advantage of allowing rapid changes in the proteome, which is of particular importance when cells are faced with stressful conditions [83].”
Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis (2017, background): “IRESs can act by various mechanisms, including the formation of RNA structures, Watson-Crick base pairing with the 18S ribosomal RNA, and often in cooperation with IRES-transacting factors (ITAFs) (Komar and Hatzoglou, 2011); moreover, putative cellular IRESs have been suggested to play crucial role”