Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes

By D. Shen, Lynn M. Pouliot, Matthew D. Hall, Michael M. Gottesman. Pharmacological Reviews, 2012

864 citations recorded by the source corpus.

Subfields: Cell Biology, Nutrition and Dietetics, Oncology

View Paper: https://www.semanticscholar.org/paper/b8ce38ee6243790e9b16933fb26f3111fde337f7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Guido Kroemer
2. L. Galluzzi
3. Rebecca S. Y. Wong

In Nutrition and Dietetics

1. Guido Kroemer

In Oncology

1. Guido Kroemer
2. L. Galluzzi
3. M. Castedo
4. Zhesheng Chen
5. Rebecca S. Y. Wong

Citations in the corpus

• Systems biology of cisplatin resistance: past, present and future (2014, background): “CDDP resistance is often multifactorial, as it relies on the simultaneous activation of multiple, non-redundant molecular circuitries (Figure 2).(48,203)”
• Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies. (2016, background): “For example, an observed decrease in sensitivity to therapeutic substances (such as cisplatin) that are not P-gp substrates in P-gp-overexpressing tumor cells suggested that ABC transporters may play additional roles in regulatory pathways (Shen et al., 2012).”