Non-coding RNA.

By John S. Mattick, Igor V. Makunin. Human Molecular Genetics, 2006

2,549 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f926047141eabe82841a545e3381a369f7ba7436

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Citations in the corpus

The Genetic Signatures of Noncoding RNAs (2009, background): “Many miRNAs are highly conserved from nematodes to humans, whereas others are primate-specific, and their full repertoire remains to be determined [4,69,70].”
The Role of MicroRNAs in Human Diseases (2010, background): “For example, miRNAs and a large set of ncRNAs including: Air, H19, Ipw, NTT, Tsix and XIST in mammals (known as ‘‘gene regulators’’) have been proposed to have different functions ranging from imprinting to inactivation of X-chromosome in mammals (17) .”
Maximizing mouse cancer models (2007, background): “Indeed, many transcription factor and microRNA binding sites are present within untranslated regions of a gen”
Induced ncRNAs Allosterically Modify RNA Binding Proteins in cis to Inhibit Transcription (2008, background): “S5b), while the N-terminus (1-211) interacted with CBP (Fig.”
Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA (2017, background): “With the discovery of all of these forms of RNA, the genome can no longer be thought of as a linear array of distinct transcriptional units, but rather is ‘‘an amazingly complex landscape of interlacing and overlapping transcripts, not only on opposite strands, but also on the same strand, so that t”
Evolution and functions of long noncoding RNAs. (2009, background): “…loci tend to be expressed at high levels, whereas larger numbers of non-protein-coding loci are expressed, sometimes in a regulated manner (see below), at lower levels, suggesting that noncoding RNAs represent cryptic signals that control complex developmental processes (Mattick and Makunin, 2006).”
Discovering Sequence Motifs with Arbitrary Insertions and Deletions (2008, background): “RNA molecules frequently contain functional sites with motifs that mediate, for example, subcellular localization and degradation.”
The lncLocator: a subcellular localization predictor for long non‐coding RNAs based on a stacked ensemble classifier (2018, neutral): “There are various types of ncRNAs, including rRNAs, tRNAs, microRNAs (miRNAs), small nuclear RNAs (snRNAs), small nucleolar RNAs (snoRNAs), small interfering RNAs (siRNAs), long non-coding RNAs (lncRNAs), etc. (Mattick and Makunin, 2006).”
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer (2017, background): “For instance, rRNAs and tRNAs participate in mRNA translation, snoRNAs (small nucleolar RNAs) are involved in rRNA modiﬁcations, snRNAs (small nuclear RNAs) drive splicing and both miRNAs (micro RNA) and siRNAs (small interfering RNA) regulate gene expression [52].”
CPC2: a fast and accurate coding potential calculator based on sequence intrinsic features (2017, background): “Recent studies have well demonstrated that non-coding RNAs (ncRNAs) are pervasively transcribed from plant to animal genomes (1–4).”
Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “However, many other types of non-coding RNA (ncRNA) molecules have been discovered and these may be just the “tip of the iceberg” [2060, 2061, 2062, 2063, 2064, 2065, 2066].”
Repetitive Elements May Comprise Over Two-Thirds of the Human Genome (2011, background): “By contrast, only about 5–10% of mammalian and vertebrate genome sequences comprise genes and known functional elements [1,2,3].”