Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

By J. Badner, E. Gershon. Molecular Psychiatry, 2002

844 citations recorded by the source corpus.

Subfields: Genetics

View Paper: https://www.semanticscholar.org/paper/f8443109bc4f0c8dc26bf70904d1f73249e83638

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In Genetics

1. Daniel R. Weinberger
2. Matthew McGue
3. Francis J. McMahon
4. Peter M. Visscher
5. Cathryn M. Lewis
6. Douglas F. Levinson
7. T. Bouchard
8. Michael E. Goddard

Citations in the corpus

• Neuregulin 1 in neural development, synaptic plasticity and schizophrenia (2008, background): “Meta-analyses of whole-genome linkage scans identified 8p as a susceptibility locus for the disorde”
• Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (2003, methodology): “Previous attempts at meta-analysis have included a multiple scan probability (MSP) analysis (Badner and Gershon 2002), which combines P values across scans in regions with clusters of positive scores after adjusting for the size of the region, and a preliminary GSMA (Segurado and Gill 2001).”
• Genetic and environmental influences on human psychological differences. (2003, background): “…linkage studies of schizophrenia and bipolar disorder found the strongest evidence for susceptibility loci on the short arm of chromosome 8, and the long arms of chromosomes 13 and 22 for schizophrenia, and the long arms of chromosome 13 and 22 for bipolar disorder (Badner and Gershon, 2002).”
• Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. (2004, background): “The COMT gene is located in chromosome 22q11, one of the principal loci linked to schizophrenia (Badner and Gershon 2002), and in the DiGeorge–velocardiofacial syndrome hemideletion.”
• Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database (2008, neutral): “Genome-wide linkage analyses have identified several chromosomal regions thought to harbor schizophrenia genes, but only a few overlap across studie”
• The genetics of schizophrenia and bipolar disorder: dissecting psychosis (2005, background): “Badner and Gershon 13 found the strongest evidence for susceptibility loci on 13q and 22q when examining seven published genome scans for bipolar disorder.”
• The Catechol-O-Methyltransferase Polymorphism: Relations to the Tonic–Phasic Dopamine Hypothesis and Neuropsychiatric Phenotypes (2004, background): “This conceptualization seemed compatible with the presence of schizophreniform symptoms in some patients with microdeletions on chromosome 22q11 that involve the COMT gene, and indeed a recent metaanalysis of genome-wide linkage studies identified chromosome 22q as one of only three loci that contin”
• Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. (2003, methodology): “Badner and Gershon (2002a) reported a meta-analysis of published SCZ genome scans using their multiple scan probability (MSP) method (Badner and Gershon 2002b), which combines P values across scans in regions with clusters of positive scores after adjusting for the size of the region.”