Population Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in Critically Ill Patients from a Multicenter Study Provide Dosing Suggestions for Various Categories of Patients

By S. Garonzik, Jian Li, V. Thamlikitkul, David L. Paterson, S. Shoham, J. Jacob, F. Silveira, Alan Forrest, Roger L. Nation. Antimicrobial Agents and Chemotherapy, 2011

691 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Medicine, Pharmacology

View Paper: https://www.semanticscholar.org/paper/f7f879962374170ca4e1b6870698bac7e9338b8e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. P. Nordmann
2. J. Pitout

In Molecular Medicine

1. L. Poirel
2. P. Nordmann
3. J. Pitout
4. A. Jayol
5. K. Bush
6. P. Bradford
7. F. Codjoe
8. E. Donkor

In Pharmacology

1. P. Nordmann
2. L. Poirel
3. J. Pitout

Citations in the corpus

• Polymyxins: Antibacterial Activity, Susceptibility Testing, and Resistance Mechanisms Encoded by Plasmids or Chromosomes (2017, methodology): “Moreover, dosing regimens given by manufacturers are often discordant with the dosing regimens recommended by the recent literature (21, 34, 41).”
• Carbapenemases in Klebsiella pneumoniae and Other Enterobacteriaceae: an Evolving Crisis of Global Dimensions (2012, background): “It is therefore critical to administer an adequate total daily dosage of colistin to critically ill patients, particularly to those who are on renal replacement therapy, in order to accomplish efficacious levels according to current recommendations (97).”
• Carbapenemase-Producing Klebsiella pneumoniae, a Key Pathogen Set for Global Nosocomial Dominance (2015, background): “The current recommendations include a loading dose and a total standard dose of 9 to 10 million international units daily divided into two or three doses (113).”