Gene Body-Specific Methylation on the Active X Chromosome

By A. Hellman, A. Chess. Science, 2007

755 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/f7c40bd0112b5c9efe530d3fe0d450229e570234

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Citations in the corpus

Neuronal activity modifies DNA methylation landscape in the adult brain (2011, background): “, emerging evidence suggests diverse roles of DNA methylation in various contexts, including promoting gene expressio”
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains (2011, background): “4c ), indicating that observations about differential methylation at gene bodie”
DNA methylation landscapes: provocative insights from epigenomics (2008, background): “Using SNPs to distinguish homologous X chromosomes on microarrays, Hellman and co-worker”
Distinct Epigenomic Landscapes of Pluripotent and Lineage-committed Human Cells (2010, background): “H3K36me3 and DNA methylation have been described in exons of transcribed gene bodies (Ball et al., 2009; Hellman and Chess, 2007; Kolasinska-Zwierz et al., 2009).”
Epigenetic modifications and human disease (2010, background): “Gene body methylation is common in ubiquitously expressed genes and is positively correlated with gene expressio”
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). (2008, background): “This is reminiscent of a recent report of hypomethylation at gene promoters and hypermethylation of gene bodies on the active X-chromosome in humans (Hellman and Chess 2007).”
DNA Methylation and Its Basic Function (2013, background): “Evidence suggests that DNA methylation of the gene body is associated with a higher level of gene expression in dividing cells (Hellman and Chess, 2007; Ball et al, 2009; Aran et al, 2011).”
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos (2014, neutral): “1E; Hellman and Chess 2007).”
Next-Generation Genomics: an Integrative Approach (2010, positive): “Allele-specific DNA methylation, which can now be assayed at genome-scale, can also suggest potential mechanisms for monoallelic expression or repression, such as imprinting (see also below”
Epigenetics and the biological definition of gene x environment interactions. (2010, background): “The silencing of the X-chromosome is associated with DNA methylation (Mohandas, Sparkes, & Shapiro, 1981; Riggs & Pfeifer, 1992; see Hellman & Chess, 2007, for a more current update).”
DNA methylation: The nuts and bolts of repression (2007, neutral): “1) (Jones, 1999; Hellman and Chess, 2007).”
Gene Body Methylation can alter Gene Expression and is a Therapeutic Target in Cancer (2014, background): “…that the bodies of actively expressed genes, particularly those located on the active X chromosome, show increased DNA methylation relative to their inactive counterparts, the issue of whether this causally affects transcription rates has been very difficult to discern (Hellman and Chess, 2007).”