Metabolic Profiling Allows Comprehensive Phenotyping of Genetically or Environmentally Modified Plant Systems

By Ute Roessner, Alexander Luedemann, Doreen Brust, Oliver Fiehn, T. Linke, Lothar Willmitzer, Alisdair R. Fernie. The Plant Cell, 2001

1,012 citations recorded by the source corpus.

Subfields: Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/f706977179cefec052b91a1270534d007eacd2dd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Spectroscopy

Citations in the corpus

VANTED: A system for advanced data analysis and visualization in the context of biological networks (2006, methodology): “This observation is in accordance with a previous study in which these correlations were shown to be the strongest ones in a different data set [1].”
Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry (2007, background): “The second alignment is then performed as described for the smaller retention corrected search window (13).”
Metabolomics – the link between genotypes and phenotypes (2004, methodology): “GC/MS analyses were also used for comprehensively studying metabolism in potato tubers (Roessner et al., 2001).”
Parallel analysis of transcript and metabolic profiles: a new approach in systems biology (2003, methodology): “…weeks after transfer to the greenhouse were markedly different from those harvested at other developmental stages, the fact remains that transcriptional variation during development is greater than that after a relatively severe genetic perturbation of primary metabolism (Roessner et al. , 2001).”
GC–MS libraries for the rapid identification of metabolites in complex biological samples (2005, methodology): “Frequently, the identity of previously non-identified MSTs will be discovered and the question will arise if these MSTs were found in previous experiments [7,16,22,23] or by other labora-”
Clinical Applications of Metabolomics in Oncology: A Review (2009, background): “known or unknown, within or associated with a particular metabolic pathway (5, 6); and (c) target isotope-based analysis, which focuses on a particular segment of the metabolome by analyzing only a few selected metabolites that comprise a specific biochemical pathway (7).”
Metabolomics for functional genomics, systems biology, and biotechnology. (2010, methodology): “, glucose and fructose) exist whose levels show high correlation coefficients among the fluctuations of biological replicates (50, 156, 214).”
Novel genetic mapping tools in plants: SNPs and LD-based approaches (2002, background): “Metabolic profiling techniques that have recently been developed promise that detailed analysis of the biochemical basis of many traits of agronomic interest will become reality [ 41 ].”
Metabolite analysis for the comparison of irrigated and non-irrigated field grown tomato of varying genotype (2007, methodology): “GC was performed on a 5MS column (Varian Deutschland GmbH, Darmstadt, Germany), using the exact same conditions defined in Roessner et al. (2001) .”
Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement (2006, methodology): “To explore the genetic basis of tomato fruit biochemistry, here we have used a high-throughput gas chromatography/mass spectrometry metabolite profiling protoco”