Metabolomics for functional genomics, systems biology, and biotechnology.

By Kazuki Saito, Fumio Matsuda. Annual Review of Plant Biology, 2010

706 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a78e91610c318fcef63fd9529d49b6a2645570ad

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Citations in the corpus

Mechanism of Salinity Tolerance in Plants: Physiological, Biochemical, and Molecular Characterization (2014, background): “Higher plants have a remarkable ability to synthesize a vast array of metabolites that differ in chemical complexity and biological functions playing an indispensible role in stress alleviation [229, 230].”
Ecological metabolomics: overview of current developments and future challenges (2011, background): “…directly (Fiehn et al. 2000), whereas transcriptomics and proteomics analyze the way genome expression translates to biological response, thus allowing us to detect the genes that are expressed in one determined moment (Colebatch et al. 2004; Fridman and Pichersky 2005; Saito and Matsuda 2010).”
Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids (2013, background): “Subsequent omics profil- ing using these genetically engineered plants has led to the identification of new functions of biosynthetic genes and the clarification of biosynthetic pathways (Fukushima et al., 2009; Saito and Matsuda, 2010).”
KNApSAcK family databases: integrated metabolite-plant species databases for multifaceted plant research. (2012, positive): “Thus, the total number of metabolites in plant species can be estimated as 1,060,000 (=98,800/20741 223,300), comparable with the reported range for metabolite number (200,000– 1,000,000; Saito and Matsuda 2010).”
The use of metabolomics to dissect plant responses to abiotic stresses (2012, neutral): “5,000) [2–5].”
The flavonoid biosynthetic pathway in Arabidopsis: structural and genetic diversity. (2013, neutral): “thaliana is estimated to exceed 5000 [5,6].”
Rewiring of the Fruit Metabolome in Tomato Breeding. (2018, background): “While metabolome coverage is not as comprehensive (Fernie et al., 2004), advances in highthroughput metabolic profiling have rendered metabolomics an important tool for both fundamental and applied research (Saito and Matsuda, 2010).”
Harnessing the complexity of metabolomic data with chemometrics (2014, background): “sis, cancer research, diabetes, responses to environmental stress [2], drug metabolism, natural product discovery and functional genomics [3].”
RIKEN tandem mass spectral database (ReSpect) for phytochemicals: a plant-specific MS/MS-based data resource and database. (2012, methodology): “…chromatographic separation and mass spectrometry (MS) are widely used for high throughput and high sensitivity/selectivity analysis of a broad range of phytochemicals (Fiehn et al., 2000; Guy et al., 2008; Hall et al., 2008; Saito and Matsuda, 2010; Schauer and Fernie, 2006; Sumner et al., 2003).”
Metabolomics for Investigating Physiological and Pathophysiological Processes. (2019, background): “Individual plants are thought to have 30,000–80,000 metabolites, with the entire plant kingdom consisting of between 200,000 and 1,000,000 metabolites (200, 404).”