The genetic theory of adaptation: a brief history

By H. Allen Orr. Nature reviews genetics, 2005

1,150 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Genetics

View Paper: https://www.semanticscholar.org/paper/f588d1b2577f25e2006227abfa227fb7720c3def

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Citations in the corpus

Life is Physics: Evolution as a Collective Phenomenon Far From Equilibrium (2010, background): “How these dynamics play out when the spatial structure of microbial populations is included is a fascinating question, bringing together genome dynamics, ecosystem 6 dynamics and population dynamics in a way that has not yet been explored.”
Divergent selection and heterogeneous genomic divergence (2009, background): “…1986; King & Jukes 1969; Ohta 1992, 2002), variable mutation rates (Balloux & LugonMoulin 2002; Hedrick 2005; Noor & Feder 2006), the genomic distribution and effect size of genes under selection (Orr 2005), and chromosomal structure (Noor et al. 2001; Rieseberg 2001; Ortiz-Barrientos et al. 2002).”
Regulatory Flexibility (2013, background): “This form of measurement appears to be especially applicable to highly aversive or traumatic life events (Bonanno, 2004, 2005).”
Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence (2011, result): “For most of the twentieth century, phenotypic divergence was assumed to result from the fixation of many mutations of small effect, but this view began to change circa 1980 when quantitative geneticists uncovered 'major' effect loci underlying phenotypic variatio”
Adaptation, migration or extirpation: climate change outcomes for tree populations (2008, background): “…in adaptation to climate in natural hybrid zones spanning steep climatic gradients may yield considerable knowledge about genes and traits involved in rapid adaptation to climate, and will allow the assessment of the potential for transgressive segregation to produce phenotypes for new climates.”
Pseudomonas aeruginosa population structure revisited under environmental focus (2010, background): “Irrespectively, mutation is a major source of variation on which selection then can act and, thus, lead to adaptation [the process by which a population becomes better suited to its environment (Orr, 2005)].”
Fitness and its role in evolutionary genetics (2009, background): “Fitness landscapes Many recent discussions of molecular evolution by natural selection have focused on evolution on so-called fitness landscape”
Stickleback research: the now and the next (2013, background): “Much debate has surrounded the extent to which adaptation to new environments proceeds through changes in just a few genomic regions or in many regions spaced throughout the genome (Orr, 2005).”