Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology

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Provenance and temporal variations in selected flavonoids in leaves of Cyclocarya paliurus (2011, background): “Flavonoids are a large group of phenolic plant constituents, and more than 6000 flavonoids have been identified; however, the bioavailability of flavonoids varies greatly between different subgroups and compounds (Erlund, 2004).”
Hesperetin-Loaded Solid Lipid Nanoparticles and Nanostructure Lipid Carriers for Food Fortification: Preparation, Characterization, and Modeling (2013, background): “…of Mashhad (FUM), Mashhad, Iran e-mail: milad.fathi@stu-mail.um.ac.ir J. Varshosaz Department of Pharmaceutics, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran 2000), heart attack (Erlund 2004), and blood pressure (Borradaile et al. 1999; Horcajada and Coxam 2004).”
Natural Antioxidants in Foods and Medicinal Plants: Extraction, Assessment and Resources (2017, background): “The richest dietary source are soybean and soy products [186,187].”
A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. (2007, background): “Although the potential for biliary recirculation could theoretically contribute to an extended bioavailability (Erlund, 2004; Abrahamse et al., 2005), it is dependent on the colonic deconjugation of the quercetin derivatives to the aglycone.”