A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties.

By M. Harwood, B. Danielewska-Nikiel, J. Borzelleca, G. Flamm, G. Williams, T. Lines. Food and Chemical Toxicology, 2007

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Quercetin, Inflammation and Immunity (2016, background): “Additional literature suggests that isoquercetin (glycosylated quercetin) is more completely absorbed than quercetin in the aglycone form, and that the simultaneous ingestion of quercetin with vitamin C, folate and additional flavonoids improves bioavailability [38,42].”
A review on the dietary flavonoid kaempferol. (2011, background): “Although numerous in vitro studies suggest that kaempferol and quercetin may be genotoxic and carcinogenic, these effects have not been demonstrated in animal studies [344-346].”
Antioxidant and anti-inflammatory activities of quercetin and its derivatives (2018, methodology): “Dietary supplementation with quercetin and its addition into food is highly supported by data on its safety (Harwood et al., 2007; Okamoto, 2005).”
The flavonoid quercetin in disease prevention and therapy: facts and fancies. (2012, background): “Earlier studies in the 1970s recognized quercetin as genotoxic by standard tests (reviewed in [11]).”