Renal clearance of quantum dots

By Hak Soo Choi, Wenhao Liu, P. Misra, Eiichi Tanaka, J. P. Zimmer, Binil Itty Ipe, Moungi G. Bawendi, John V. Frangioni. Nature Biotechnology, 2007

4,107 citations recorded by the source corpus.

Subfields: Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/f5075d1788bf0bf6488dda607b388378d86f5b21

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In Materials Chemistry

Citations in the corpus

Endocytosis and exocytosis of nanoparticles in mammalian cells (2014, background): “However, these drug delivery nanosystems have shown some limitations regarding the toxicity of the nanoscale materials in the body.(4,5) In order to reduce their toxicity, it is crucial to study endocytosis, exocytosis, and clearance mechanisms for nanoparticles released from the nanoparticle–drug c”
Effect of gold nanoparticle aggregation on cell uptake and toxicity. (2011, background): “ance via the kidney was dependent upon size.(11,12) When working with nanoparticles, it is always crucial to quantify the morphology,”
Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine (2012, background): “Highly magnetic materials such as cobalt and nickel are susceptible to oxidation and are toxic; hence, they are of little interest [26-28].”
Delivering nanomedicine to solid tumors (2010, background): “Particles with a hydrodynamic diameter smaller than 5–6 nm are rapidly cleared by the kidney (blood half-life”
Nanoparticles for Biomedical Imaging: Fundamentals of Clinical Translation (2010, background): “Depending on the organic coating surrounding the NPs, nonspecific adsorption of plasma proteins, mostly albumin, can also increase effective HD and thus extravasation.(9,20) Only neutral or certain hydrophilic surfaces (eg, zwitterionic) and neutral surfaces can prevent plasma protein adsorption.”
Design Considerations for Tumor-Targeted Nanoparticles (2009, neutral): “d, The avb3-positive M21 tumour (T(þ)) and avb3-negative M21-L tumour (T(2)) are shown.”
Multistage nanoparticle delivery system for deep penetration into tumor tissue (2011, background): “However, despite the improved pharmacokinetic properties (7) and reduced adverse effects, these drugs have provided only modest survival benefits (1, 8–10).”