How proteins move lipids and lipids move proteins

By H. Sprong, P. Sluijs, G. Meer. Nature reviews. Molecular cell biology, 2001

594 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

A class of membrane proteins shaping the tubular endoplasmic reticulum. (2006, unknown): “For example, the high curvature in cross-sections of the tubules could be generated if the two leaflets of a membrane had different lipid compositions (for review, see Farsad and De Camilli, 2003; Sprong et al., 2001).”
Modelling fluid deformable surfaces with an emphasis on biological interfaces (2018, background): “…membranes is essential for cell function; it is required during cell motility and migration (Arroyo et al. 2012; Lieber et al. 2015), membrane trafficking (Sprong et al. 2001; Rustom et al. 2004), or to enable the mechano-adaptation of cells to stress (Staykova et al. 2013; Kosmalska et al. 2015).”
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. (2002, background): “Alternatively, this Ptch activity could influence membrane structure and Smo trafficking (Sprong et al. 2001); a shift in Smo localization might then be accompanied by activity-modulating changes in the molecular composition of specific subcellular compartments (Sprong et al. 2001).”
Role of cholesterol and lipid organization in disease (2005, background): “First, many membrane proteins prefer to associate with a particular type of organization, and this will lead to their physical separation in bilayers with coexisting lipid phase”