Bats Are Natural Reservoirs of SARS-Like Coronaviruses

By Wendong Li, Zhengli Shi, Meng Yu, Wuze Ren, Craig E. Smith, J. Epstein, Hanzhong Wang, G. Crameri, Zhìhóng Hú, Huajun Zhang and 7 more. Science, 2005

2,516 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/f270438ddc983d3b61976fb24e7833e7cadd1ad8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Animal Science and Zoology

In Epidemiology

In Infectious Diseases

Citations in the corpus

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein (2020, background): “The recurrent spillovers of coronaviruses in humans along with detection of numerous coronaviruses in bats, including many SARS-related coronaviruses (SARSr-CoVs), suggest that future zoonotic transmission events may continue (Anthony et al., 2017; Ge et al., 2013; Hu et al., 2017; Li et al., 2005b;”
A decade after SARS: Strategies to control emerging coronaviruses (2013, background): “Many of these viruses infect various bats and other animal species, and several are phylogenetically similar to known pathogenic human coronaviruses [4] [5] [6] [7] [8] [9] [10] [11] [12] [13] , which suggests that additional emergence events are highly likely to occur.”
Title: Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice (2020, neutral): “All three viruses presumably originated in bats (4), with SARS-CoV and MERS-CoV adapting to intermediary animal hosts before jumping to humans.”
Coronavirus Pathogenesis (2011, background): “As discussed above, many SARS-CoV like viruses have been isolated from bats, leading to the belief that the reservoir for SARS-CoV is the bat (Lau et al., 2005; Li et al., 2005b).”
Molecular diversity of coronaviruses in bats (2006, background): “…bats (Rhinolophus sinicus) in our locality (Lau et al., 2005), whereas in some other provinces in China, it was detected in some other species of horseshoe bats of the same genus (Rhinolophus ferrumequinum, Rhinolophus macrotis, Rhinolophus pearsoni and Rhinolophus pussilus) (Li et al., 2005).”
Human Coronavirus: Host-Pathogen Interaction. (2019, background): “The etiologic agent was identified as SARS-CoV, a zoonotic betacoronavirus originated in horseshoe bats that later adapted to infect the intermediate host palm civet and ultimately humans (64).”
Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study (2020, background): “Detection of SARS-CoV in Himalyan palm civets and horseshoe bats identified 29 nucleotide sequences that helped trace the origins of SARS-CoV isolates in humans to these intermediary species [13, 24, 38, 77].”
Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? (2019, background): “The 2002–2003 SARS pandemic was caused by a coronavirus that emerged from bats (first reservoir) [25] to infect palm civets (intermediary reservoir) and then humans [215].”
Coronavirus Diversity, Phylogeny and Interspecies Jumping (2009, background): “The discovery of bat-SARS-CoV has marked the beginning of the race of coronavirus hunting in bats (31, 34).”