Aurora B-mediated abscission checkpoint protects against tetraploidization.

By Patrick Steigemann, C. Wurzenberger, Michael H. A. Schmitz, Michael Held, Julien Guizetti, Sandra Maar, Daniel Gerlich. Cell, 2009

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Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis (2009, background): “A recent study has proposed an Aurora B kinase-dependent ' Abscission checkpoint' in human cells that delays the completion of cytokinesis in response to chromosome bridge”
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development (2011, background): “During cytokinesis, aurora B is localized to the midbody remnant where its local inactivation is crucial for completion of abscission (Guse et al., 2005; Steigemann et al., 2009).”
Shared and separate functions of polo-like kinases and aurora kinases in cancer (2010, background): “Finally, aurora kinase B was also implicated in a novel abscission checkpoint, sensing unsegregated chromatin at the cleavage site and preventing abscission until chromosome bridges have been resolve”