The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density‐dependency of the quorum sensing hierarchy, regulates rhl‐dependent genes at the onset of stationary phase and can be…

By Steve Diggle, Klaus Winzer, S. R. Chhabra, Kathryn E. Worrall, Miguel Cámara, P. Williams. Molecular Microbiology, 2003

594 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/eca17691026ef26be70106fd318ace20bc912cf2

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The hierarchy quorum sensing network in Pseudomonas aeruginosa (2014, background): “, 2002), but the mutants failed to respond to PQS (Diggle et al., 2003; Farrow et al., 2008; Gallagher et al., 2002), and did not express the PQS-controlled phenotypes such as pyocyanin and PA-IL lectin production.”
The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa (2006, background): “The requirement of PQS and PqsE has been well established for expression of phzA1-G1 (Diggle et al., 2003; Deziel et al., 2005).”
The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa (2012, background): “RsaL binds simultaneously with the 3-oxo-C12-HSL–LasR complex to the lasI promoter (163), inhibiting its transcription, while in parallel it controls the repression of AHL-related virulence by directly binding to the promoters of pyocyanin and hydrogen cyanide (HCN) genes (165).”
Microbial fuel cells: An overview of current technology (2019, background): “28 protozoa), an electron shuttle and a key sensing molecule to upregulate the transcription of quorum sensing genes, leading to biofilm formation [237-245].”
Rhamnolipids: Detection, Analysis, Biosynthesis, Genetic Regulation, and Bioengineering of Production (2011, background): “, mvfR or pqsE ) or lasR mutants still express rhlAB and produce RLs, but at reduced or delayed rates (Dekimpe and Déziel 2009; Déziel et al. 2005; Diggle et al. 2003; Ochsner and Reiser 1995).”
Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules. (2009, background): “com addition of the pseudomonas quinolone signal (PQS; 2heptyl-3-hydroxy-4-quinolone; Figure 1) to the growth medium at the time of inoculation [24].”
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms (2006, background): “In accordance with Diggle et al. (2003) the pqsA mutant could not form structured biofilms; in our flow chamber set-up it formed only a flat and thin biofilm (Fig.”
Look who's talking: communication and quorum sensing in the bacterial world (2007, background): “This 4-quinolone is required for the production of rhl-dependent exoproducts at the onset of stationary phase (Pesci et al. 1999; Diggle et al. 2003) but, in contrast to the AHLs, is capable of overcoming the cell density but not growth phasedependent production of P.”