The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa

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Efflux-Mediated Drug Resistance in Bacteria: an Update (2009, background): “The phenazine pyocyanin is a physiological signalling factor for the up-regulation of several quorum sensing-controlled genes including those encodingMexHI-OpmD pump.([642]) Overexpression of the quorum sensing regulator SdiA in E.”
The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa (2012, background): “The absence of sox boxes in the remaining genes of the PYO stimulon indicates that additional regulatory factors in this signaling cascade remain to be elucidated (48).”
Microbial fuel cells: An overview of current technology (2019, background): “28 protozoa), an electron shuttle and a key sensing molecule to upregulate the transcription of quorum sensing genes, leading to biofilm formation [237-245].”
Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules. (2009, background): “Intriguingly, pyocyanin also functions as the terminal signal for the expression the PqsR/PQS-regulated genes such as the mexGHI-ompD efflux pump and PA2274 (a putative mono-oxygenase) [40].”
Exoelectrogenic bacteria that power microbial fuel cells (2009, background): “aeruginosa produces pyocyanin, a chemical that is a signal for the upregulation of quorum sensing-controlled gene”