Regulatory T cells in transplantation tolerance.

By H. Waldmann, L. Graça, E. Adams, P. Fairchild, S. Cobbold. Current Topics in Microbiology and Immunology, 2005

862 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/ec4d9c7ac660768147f5ea2bbb69414e1fc51f64

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In Immunology

Citations in the corpus

Tim-3 inhibits T helper type 1–mediated auto- and alloimmune responses and promotes immunological tolerance (2003, background): “Although the exact mechanism of action has not been defined, both cell-to-cell contact interactions and soluble factors have been linked to their immunosuppressive functio”
Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion cases. (2004, background): “Recently it has been demonstrated that regulatory T (Treg) cells have a role in the induction of transplantation tolerance (Graca et al., 2002; Karim et al., 2002; Bach, 2003; Bluestone and Abbans, 2003; Word and Sakaguchi, 2003).”
Mesenchymal stem cells avoid allogeneic rejection (2005, background): “Recipient antigen presenting cells (APC) such as dendritic cells (DC) process alloantigen into peptides and present these to naive T cells on self-MHC molecules [12].”
Regulatory T cell lineage specification by the forkhead transcription factor foxp3. (2005, background): “…only demonstrates the remarkable immunosuppressive potential of CD4+CD25+ TR cells, but does not prove a is highlighted by the ability of CD4+CD25+ TR cells to suppress immune pathology not resulting from CD4+CD25+ TR cell defects such as in allograft transplantation (Wood and Sakaguchi, 2003).”
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans (2006, background): “cell–cell contact mechanisms for mediating suppressive activity (4, 5).”