Context, ambiguity, and unlearning: sources of relapse after behavioral extinction.

By M. Bouton. Biological Psychiatry, 2002

1,602 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/eb6297b69163f08fb845dfae17461505ff8a957f

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Prefrontal mechanisms in extinction of conditioned fear. (2006, neutral): “Brain-imaging studies of PTSD patients show reduced activity (Bremner 2002; Shin et al 2004) and reduced volume (Rauch et al 2003) in the perigenual prefrontal cortex, an area that is homologous with extinctionrelated regions of rodent mPFC (Milad et al 2006).”
Looking Beyond Content: Skill Development for Engineers (2008, background): “cognitive science on conditioning, attempts to eliminate conditioning (extinction), and its reemergence (relapse) (Bouton, 2002).”
Neurocognitive mechanisms of anxiety: an integrative account. (2007, background): “Are there common neurocognitive mechanisms underlying the attentional, interpretative and associative processing of threat? It has been argued that fear extinction results in the CS becoming, in effect, an emotionally ambiguous stimulus linked to representations of both threat (from acquisition) and”
Memory processes in classical conditioning. (2004, background): “Ultimately, it is almost universally held that ‘context’ can be provided by many kinds of cues [64,95,96], and all should therefore be kept in mind.”
Contributions of the amygdala to emotion processing: from animal models to human behavior. (2005, methodology): “One technique for altering learned emotional responses, especially those established as Pavlovian associations, is experimental extinction (Myers and Davis, 2002; Morgan et al., 1993; Bouton, 2002; Sotres-Bayon et al., 2004).”
Team adaptation in context: An integrated conceptual model and meta-analytic review (2017, background): “Learning behavior occurs when a team engages in activities that create iterative and shared action-reflection experiences (Vashdi et al., 2013), such as experimentation or adding new information to one’s repertoire (Bouton, 2002).”
Fear extinction and relapse: state of the art. (2013, background): “Some studies have replicated critical results in appetitive and instrumental conditioning in rats, showing generalizability of the retrieval model of extinction (Bouton 2002).”
The Fear-Avoidance Model of Musculoskeletal Pain: Current State of Scientific Evidence (2006, background): “Second, during extinction procedures, no unlearning takes place, but rather new learning that leaves the original association between the conditioned and unconditioned stimulus intact, making relapse likely (Bouton, 2002).”
Distinct dopamine receptor pathways underlie the temporal sensitivity of associative learning (2019, background): “A learned olfactory association can be weakened if an animal encounters the odor in the absence of the anticipated reinforcement or the reinforcement in the absence of the conditioned odor, violating the expected contingency between these cues (Aso and Rubin, 2016; Berry et al., 2012; Bouton, 2002; ”
Extinction learning in humans: role of the amygdala and vmPFC. (2004, background): “…of time (spontaneous recovery), the presenta-Summary tion of the US alone (reinstatement), or if the animal is placed in the context of initial learning (renewal; seeUnderstanding how fears are acquired is an important step in translating basic research to the treatment Bouton, 2002, for a review).”
A unified framework for addiction: Vulnerabilities in the decision process (2008, background): “Following from the hypothesis that extinction follows from a reinterpretation of situations (Bouton 2002; Capaldi 1957; Quirk et al. 2006; Redish et al. 2007), this would suggest a difficulty in extinguishing drug-taking.”
The Cruelest Cure? Ethical Issues in the Implementation of Exposure-Based Treatments (2009, neutral): “…notion by many practitioners that exposure therapy is uncomplicated, there is an abundance of experimental psychopathology research highlighting mediators and moderations that contribute to the complexity of the mechanisms that underlie successful exposure-based treatment (see Bouton, 2002).”
AMYGDALA MICROCIRCUITS CONTROLLING LEARNED FEAR (2014, background): “Third, extinction is context-dependent such that fear responses return if the CS is presented in a different context than the one where extinction training occurred, a phenomenon known as fear renewal (Bouton, 2002, 2004).”