Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

By M. Blanco, G. Moreno-Bueno, D. Sarrió, A. Locascio, A. Cano, J. Palacios, M. Nieto. Oncogene, 2002

619 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e9d95a8b880a55e2146d7b7ec3232d0b9763d1be

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Citations in the corpus

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? (2007, background): “The expression of SNAI1 in breast carcinomas is associated with E-cadherin repression and metastasi”
Epithelial-mesenchymal plasticity in cancer progression and metastasis (2019, background): “In cancer, their expression leads to decreased E-cadherin level, enhanced tumor cell invasion and metastatic phenotypes in mouse tumor models and cell line studies, and is associated with poor prognosis in patients with breast, colorectal and hepatocellular carcinoma (Blanco et al., 2002; De Craene ”
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition (2004, result): “These results are consistent with a previous finding that the expression of Snail is found in biopsies that associate with malignant phenotypes from patients with ductal breast cancer, gastric cancer and hepatocellular carcinom”
Snail Mediates E-Cadherin Repression by the Recruitment of the Sin3A/Histone Deacetylase 1 (HDAC1)/HDAC2 Complex (2004, background): “Among them, the transcription factor Snail has been described as a strong repressor of E-cadherin in different murine and human carcinoma and melanoma cell lines and tumors (5, 9, 11, 13, 41, 48, 55) as well as during Drosophila and mouse embryo development (12, 25, 37, 38).”
Anoikis molecular pathways and its role in cancer progression. (2013, background): “Similar mechanism has been described for Snail-1, which has found upregulated in primary human breast carcinomas and breast tumors [19].”
Involvement of members of the cadherin superfamily in cancer. (2009, background): “High-grade breast tumors and lymphnode positive tumors consistently show strong Snail expression (Blanco et al. 2002).”
Epithelial-Mesenchymal Plasticity: A central regulator of cancer progression (2015, background): “Taking breast cancer as an example, acquisition of mesenchymal features is positively associated with more aggressive subtypes of this disease and tumor progression (Aleskandarany et al., 2014; Blanco et al., 2002; Blick et al., 2008; Choi et al., 2013).”
Snail blocks the cell cycle and confers resistance to cell death. (2004, background): “2000) and in biopsies from patients with ductal breast carcinomas (Cheng et al. 2001; Blanco et al. 2002), gastric cancer (Rosivatz et al.”
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors (2003, background): “…in human breast cancer biopsies in fact indicate a strong correlation between S ail expression, reduced E-cadherin expression and invasive grade of the tumours (Blanco et al., 2002), supporting a direct role for Snail as an E-cadherinrepressor in in vivo tumour progression of breast carcinomas.”