Store-operated calcium channels.

By A. Parekh, J. Putney. Physiological Reviews, 2005

2,512 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology, Sensory Systems

View Paper: https://www.semanticscholar.org/paper/e3a82aa7473c91bafbf986fe13c04201cec3aabf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. M. Prakriya
2. S. Feske
3. P. Hogan
4. T. Balla
5. Anjana Rao
6. Jie Zheng
7. M. Trudeau
8. S. Reddy

In Physiology

1. M. Prakriya
2. S. Feske
3. Anjana Rao
4. P. Hogan
5. T. Balla
6. S. Reddy
7. Khiem A. Tran
8. Jie Zheng

In Sensory Systems

1. S. Feske
2. M. Prakriya
3. T. Balla
4. Anjana Rao
5. P. Hogan
6. Jie Zheng
7. A. Parekh
8. M. Trudeau

Citations in the corpus

• STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels (2006, methodology): “(BAPTA and Ins(1,4,5)P3, n = 6; all others, n = 4.”
• Reactive Oxygen Species in Inflammation and Tissue Injury (2014, positive): “Since transient receptor potential (TRP) channels are believed to underlie the molecular makeup of many ROC channels (TRPC3, 6 and 7) and at least some SOC channels (TRPC1 and 4) (333), it is logical to presume that TRPC proteins are sensitive to regulation by ROS.”
• Calcium signalling in lymphocyte activation and disease (2007, background): “In lymphocytes, store-operated calcium entry (SOCE) through calcium-release-activated calcium (CRAC) channels is the main mechanism to increase intracellular Ca 2+ concentrations, and it is essential for the activation of and cytokine gene expression by T and B cells (reviewed in Ref”
• Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance (2008, background): “CRAC channels are low-conductance Ca 2+ channels with an unusually high selectivity for Ca 2+ and a characteristic inwardly rectifying current-voltage relationshi”
• Phosphoinositides: tiny lipids with giant impact on cell regulation. (2013, background): “The molecular entities that constitute this pathway had been enigmatic for a long period, with the nonspecific cation Trp (transient receptor potential) channels taking center stage (1193).”
• Handbook of ion channels (2015, background): “The channels are not sensitive to many of the common inhibitors of Cav channels, but are inhibited by imidazole antimycotics, submicromolar concentrations of lanthanides, and 2-aminoethyldiphenyl borate (2-APB), among others [28].”
• Physiology of Astroglia. (2018, neutral): “The Ca(2) -release activated Ca(2) current (ICRAC) is the principal component of the store-operated Ca(2) entry (SOCE) in the majority of nonexcitable cells (1320).”
• SOAR and the polybasic STIM1 domains gate and regulate the Orai channels (2009, neutral): “(1) Orail1+ SOAR (2) Orail1 + SOARLQ/AA (3) Orai1 + STIM1 (4) Orail1 + STIM1LQ/AA”
• Calcium and Excitation-Contraction Coupling in the Heart (2017, background): “Ca is decreased, interacts with the surface membrane channel Orai.(171) This mechanism is best characterized in nonexcitable”
• The Wellcome Prize Lecture (2003, background): “The best characterised store-operated current is ICRAC, which is found in several types of cell including mast cells, lymphocytes, macrophages, megakaryocytes and hepatocytes (Parekh & Penner, 1997; Lewis, 1999).”