Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints.

By S. Hollister, R. D. Maddox, J. Taboas. Biomaterials, 2002

735 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Mechanical Engineering, Mechanics of Materials

View Paper: https://www.semanticscholar.org/paper/e264fce6387a8a73fe459a99a0ecbe93fe408a35

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. S. Hollister
2. F. O'Brien
3. Benjamin M. Wu
4. Helena N. Chia
5. Shiwei Zhou
6. C. Lin
7. Yi Min Xie
8. Shanqing Xu

In Mechanical Engineering

1. Milan Brandt
2. M. Qian
3. Martin Leary
4. Suman Kalyan Das
5. Chao Yang
6. Yuanyuan Li
7. Yuhua Li
8. S. Hollister

In Mechanics of Materials

1. Shiwei Zhou
2. Yi Min Xie
3. Shanqing Xu
4. Martin Leary
5. Milan Brandt
6. M. Qian
7. Xiaojian Wang
8. Peter Choong

Citations in the corpus

• 3D bioactive composite scaffolds for bone tissue engineering (2017, background): “Achieving a successful balance in vivo between the properties of a scaffold favourable to cellular function, cellular viability and mechanical integrity under load bearing therefore remains challenging [65,66].”
• Computational design of tissue engineering scaffolds (2007, background): “Each approach creates a volumetric 3D design by replicating unit cells periodically in 3D space, an approach that has be used previously to design tissue engineering scaffold architecture [10,11].”
• Porous scaffold design for tissue engineering (2005, background): “Such libraries may be created either using image-based design approache”
• Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds. (2004, background): “There is also evidence that tissue synthesized in a scaffold with non-uniform pore architecture shows inferior biomechanical properties compared to tissue synthesized in a scaffold with a more uniform pore structure [13].”
• Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review. (2016, background): “There has been growing research interest in using topology optimization to design bone scaffolds and orthopaedic implants [75 , 96-100, 136-144], however significant challenges st ill remain before these concepts could be used in clinical practice.”
• Recent advances in 3D printing of biomaterials (2015, background): “These technologies enable the fabrication of multi-functional scaffolds that meet the structural, mechanical, and nutritional requirements based on optimized models [7].”
• New Developments of Ti-Based Alloys for Biomedical Applications (2014, background): “Porosity and pore geometry also affect the materials’ mechanical properties, stress shielding effect and fatigue strength [192,193].”
• Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. (2005, methodology): “The scaffold microstructure, consisting of interconnected cylindrical pores, was also created using specially written image-based design software [ 46 ].”