The versatile bacterial type IV secretion systems

By É. Cascales, P. Christie. Nature Reviews Microbiology, 2003

722 citations recorded by the source corpus.

Subfields: Endocrinology, Genetics, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/e257ed273089616432c3567579c66dd775ebd31c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. P. Christie
2. R. Wozniak
3. C. Alvarez-Martinez
4. L. Hansen
5. K. Nielsen
6. S. Sørensen
7. É. Cascales
8. Christopher M Thomas

In Genetics

1. P. Christie
2. M. Waldor
3. R. Wozniak
4. K. Nielsen
5. S. Sørensen
6. Christopher M Thomas

In Molecular Medicine

1. C. Alvarez-Martinez
2. K. Nielsen
3. P. Christie
4. J. Mecsas
5. Christopher M Thomas
6. R. Aminov

Citations in the corpus

• Genomic islands in pathogenic and environmental microorganisms (2004, background): “The tumour (crown gall) that functions as a food-producing factory represents an excellent niche for the bacteriu”
• Bacterial Secretion Systems – An overview (2016, background): “T4SSs are ancestrally related to bacterial DNA conjugation systems and can secrete a variety of substrates, including single proteins and protein–protein and DNA– protein complexes (75).”
• Biogenesis, architecture, and function of bacterial type IV secretion systems. (2005, background): “The bacterial type IV secretion (T4S) systems mediate the translocation of macromolecules across the cell envelopes of Gramnegative and Gram-positive bacteria (23, 59).”
• Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow (2010, background): “; these systems have been adapted for the transport of proteins and for DNA exchange with the environmen”
• Studying plasmid horizontal transfer in situ: a critical review (2005, background): “For detailed discussions on the mechanisms involved in T4SSs, readers are referred to recent review”
• Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems (2015, background): “, oncogenic T-DNA via the vir T4SS of Agrobacterium tumefaciens) or protein substrates directly into eukaryotic cells, wherein these effectors often perturb cell signaling to benefit bacterial survival (7, 8).”
• Mechanisms of, and Barriers to, Horizontal Gene Transfer between Bacteria (2005, background): “This structure mediates cell–cell contact to generate a junction between the bacteria and a pore through which the plasmid DNA and some donor-encoded proteins can be transported to the recipien”
• Biological Diversity of Prokaryotic Type IV Secretion Systems (2009, background): “Three types of T4SS have been described: (i) conjugation systems, defined as machines that translocate DNA substrates to recipient cells by a contact-dependent process; (ii) effector translocator systems, functioning to deliver proteins or other effector molecules to eukaryotic target cells; and (ii”