Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow

By R. Wozniak, M. Waldor. Nature Reviews Microbiology, 2010

792 citations recorded by the source corpus.

Subfields: Ecology, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/69a13d84035a94b67fad07965a8f45b552e5e225

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Citations in the corpus

Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “It is facilitated by the conjugative machinery which is encoded either by genes on autonomously replicating plasmids or by integrative conjugative elements in the chromosome (Smillie et al., 2010; Wozniak and Waldor, 2010).”
Acquired Antibiotic Resistance Genes: An Overview (2011, background): “Presumably elements like Tn916 have evolved to use different integration sites in order to increase their host range.”
CTX-M Enzymes: Origin and Diffusion (2012, background): “Part of these sequences, also known as “phage-like elements,” could have facilitated mobilization of resistance genes into the chromosome (Wozniak and Waldor, 2010; Guglielmini et al., 2011).”
The Logic of Chance: The Nature and Origin of Biological Evolution (2011, background): “Actually, among the currently wellcharacterized bacteria, conjugation is known to exist only in a minority, whereas in archaea, conjugation apparently has not been reported (Frost and Koraimann, 2010; Wozniak and Waldor, 2010).”
BugBase predicts organism-level microbiome phenotypes (2017, background): “The higher relative abundance of taxa predicted to contain mobile elements in the oral samples is driven primarily by the higher relative abundance of Proteobacteria and Actinobacteria in the oral samples that house integrative and conjugative elements (a subset of mobile elements) within the Tn916 ”
Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens. (2011, background): “The mosaic complexity of such molecules allows diverse interactions with other genetic elements, promoting exchanges that, in turn, generate more diversity (Garriss et al., 2009; Wozniak & Waldor, 2010).”
Horizontal Gene Exchange in Environmental Microbiota (2011, background): “Thus, ICEs combine the features of other MGEs, such as bacteriophages (integration into and excision from the host chromosome but no transmission by conjugation), insertion sequences (ISs), and simple transposons (integration into and excision from the chromosome but no horizontal transfer), and con”
Antimicrobial use in aquaculture re-examined: its relevance to antimicrobial resistance and to animal and human health. (2013, background): “ICE elements are genetically related to the IncA/C plasmids with the potential of genetic recombination and interactions between them that facilitate their host range and dissemination (Burrus et al., 2006; Osorio et al., 2008; Wozniak et al., 2009; Daccord et al., 2010; Wozniak and Waldor, 2010; Gu”