Structural determinants of water permeation through aquaporin-1

By K. Murata, K. Mitsuoka, T. Hirai, Thomas Walz, Peter Agre, J. Heymann, A. Engel, Y. Fujiyoshi. Nature, 2000

1,726 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/e1ee72be19c6b2d921cfc5d806dd83e386297f1c

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Citations in the corpus

The molecular basis of water transport in the brain (2003, background): “So far, crystallographic data are available only for Aqp1 (Ref”
Plant aquaporins: multifunctional water and solute channels with expanding roles. (2002, background): “…of AQP1 has been determined from electron cystallographic studies to increasingly high resolutions (e.g. Walz et al. 1995; Jap & Li 1995; Cheng et al. 1997; Walz et al. 1997; Murata et al. 2000) enabling an atomic model to be resolved at about 0·38 nm (Murata et al. 2000; Ren et al. 2001).”
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy (2003, background): “There have been a few cases of macromolecular structure analyses by electron crystallography at near atomic resolutions where density maps allowed atomic models to be buil”
Structural basis of water-specific transport through the AQP1 water channel (2001, methodology): “Models of AQP1 derived from electron crystallographic structural studies at about 4 a resolution have recently been reported; they independently confirm the presence of two membrane-inserted non-membrane-spanning helice”
Accurate determination of local defocus and specimen tilt in electron microscopy. (2003, methodology): “It can be applied to samples of different symmetry and geometry, such as two-dimensional (2D) crystals (Henderson et al., 1990; K€ uhlbrandt andWang, 1991;Mindell et al., 2001;Murata et al., 2000; Nogales et al., 1998), helical particles (Morgan et al.”
Overview of Electron Crystallography of Membrane Proteins: Crystallization and Screening Strategies Using Negative Stain Electron Microscopy (2013, methodology): “Two-dimensional crystals suitable for electron diffraction have been generated using both native (Unwin, 2005) and artificial lipids (Gonen et al., 2004), as well as non-native mixed lipids (Murata et al., 2000).”
Fluids at the Nanoscale: From Continuum to Subcontinuum Transport (2020, background): “…the molecular scale that the fluidic functions of biological systems emerge: from the giant permeability and perfect selectivity of the aquaporin (Murata et al. (2000)), to the ion specificity of KcsA channels (MacKinnon (2004)), to the mechano-sensitivity of Piezo channels (Wu et al. (2017)),…”
Ion exclusion by sub-2-nm carbon nanotube pores (2008, background): “Molecular dynamics and theoretical studies have shown single-file transport for water along the nanotube axis (12–15) that is highly reminiscent of the water wires observed in aquaporins (2, 3).”
Water Flow in the Roots of Crop Species: The Influence of Root Structure, Aquaporin Activity, and Waterlogging (2007, background): “The obverse symmetry of the pore provides AQPs with bi-directionality without rectification (Meinild et al., 1998; Murata et al., 2000).”
Aquaporins: Highly Regulated Channels Controlling Plant Water Relations1 (2014, background): “Aquaporins assemble as homo- and/or heterotetramers in the membrane, each monomer acting as independent water channel (Murata et al., 2000; Fetter et al., 2004; Bienert et al., 2012).”
Membrane transport of hydrogen peroxide. (2006, background): “30 nm [63] is also compatible with passage through aquaporins.”