Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy

By K. Yonekura, S. Maki-Yonekura, K. Namba. Nature, 2003

744 citations recorded by the source corpus.

Subfields: Developmental and Educational Psychology, Language and Linguistics

View Paper: https://www.semanticscholar.org/paper/0e4f59f7b224ade9c1f461ba9b2bb664dc861b9a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Developmental and Educational Psychology

1. O. Takeuchi
2. Gabriel Lander
3. Satoshi Uematsu
4. G. Cornelis
5. E. Nogales
6. H. Saibil
7. Shizuo Akira

In Language and Linguistics

1. O. Takeuchi
2. Gabriel Lander
3. Satoshi Uematsu
4. G. Cornelis
5. E. Nogales
6. H. Saibil
7. Shizuo Akira

Citations in the corpus

• Handbook of ion channels (2015, background): “Atomic resolution structures have been achieved for the high-symmetry well-packed complexes, such as the viral particles or tight filamentous assemblies (Yonekura et al. 2003; Yu et al. 2008).”
• Target highlights from the first post-PSI CASP experiment (CASP12, May–August 2016) (2017, neutral): “In the most commonly studied organism for flagella, Salmonella serovar Typhimurium, FliD is known to form a homopentameric complex on the tip of the flagellum, as shown in a low-resolution cryoEM structure.(7,9,10) Until recently, these data provided the only available structural insight to FliD.”
• Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome (2010, background): “To further compare these proteins at a structural level, we examined published three-dimensional structures forFliCandPrgI (18,19),andused twodifferentapproaches topredict thestructureofPrgJ (weusedour structurepredictionpipeline (20,21) as well as the 3D-jury fold recognition server (22) (Methods).”
• Automated molecular microscopy: the new Leginon system. (2005, result): “While there have been certain dramatic exceptions (Yonekura et al., 2003), the experimental evidence so far has tended to support this rule of thumb.”
• Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility (2003, background): “Flagellar filaments are composed of 11 protofilaments, which wrap together to form the filamen”
• Go Hybrid: EM, Crystallography, and Beyond (2012, methodology): “Developments in both cryoEM technology and image processing software have led to a number of reconstructions solved to better than 4 Å resolution, allowing for ab initio chain tracing [1–3].”
• Paircoil2: improved prediction of coiled coils from sequence (2006, methodology): “We have used these data to develop Paircoil2, an improved version of Paircoil, and find that it performs well in leave-family-out cross-validation and outperforms other common methods.”
• High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy (2013, background): “There are now many structures at near atomic resolution from two-dimensional (2D) crystals [13–15], helical assemblies [16,17] and icosahedral virus”
• Pathogen recognition and innate immunity. (2006, positive): “A recent analysis of the crystal structure of a Salmonella flagellin revealed that the flagellin domains are composed of N- and C-terminal a helix chains (D0), the central a helix chains (D1), and the hypervariable central region with b sheets (D2 and D3) (Yonekura et al., 2003).”
• Type IV pilus structure and bacterial pathogenicity (2004, neutral): “cgi?pid=164551080132248&page=0&pdbId=1UCU">flagella”
• The type III secretion injectisome (2006, result): “This structure is similar to the structure of the D0 portion of flagelli”