Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome

By M. Pimentel, E. Chow, Henry C. Lin. American Journal of Gastroenterology, 2000

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Postinfectious irritable bowel syndrome. (2008, background): “lactulose breath testing [45].”
Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome (2006, background): “13 ), coupled with reports of abnormal colonization of the small bowel in some patients”
Intestinal microbiota in functional bowel disorders: a Rome foundation report (2012, background): “Antibiotics Despite evidence that previous antibiotic use may be related to the development of IBS,(182) 183 and the fact that antibiotic treatment may increase the development of long-term digestive symptoms after bacterial gastroenteritis,(142) poorly absorbable antibiotics might still have therap”
Normalization of Lactulose Breath Testing Correlates With Symptom Improvement in Irritable Bowel Syndrome: A Double-Blind, Randomized, Placebo-Controlled Study (2003, methodology): “We recently reported that 78% of subjects with IBS have a positive lactulose breath test (LBT), suggesting the presence of SIBO (12).”
Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions (2010, background): “Some studies have suggested that small intestinal bacterial overgrowth (SIBO), for example, is frequent among patients with IBS”